Dysregulation of cellular membrane homeostasis as a crucial modulator of cancer risk

A Erazo‐Oliveras, M Muñoz‐Vega… - The FEBS …, 2024 - Wiley Online Library
Cellular membranes serve as an epicentre combining extracellular and cytosolic
components with membranous effectors, which together support numerous fundamental …

Scavenger receptors: novel roles in the pathogenesis of liver inflammation and cancer

DA Patten, AL Wilkinson, A O'Keeffe… - Seminars in Liver …, 2022 - thieme-connect.com
The scavenger receptor superfamily represents a highly diverse collection of evolutionarily-
conserved receptors which are known to play key roles in host homeostasis, the most …

Mutant APC reshapes Wnt signaling plasma membrane nanodomains by altering cholesterol levels via oncogenic β-catenin

A Erazo-Oliveras, M Muñoz-Vega, M Mlih… - Nature …, 2023 - nature.com
Although the role of the Wnt pathway in colon carcinogenesis has been described
previously, it has been recently demonstrated that Wnt signaling originates from highly …

Construction of a predictive model for immunotherapy efficacy in lung squamous cell carcinoma based on the degree of tumor-infiltrating immune cells and molecular …

L Yang, S Wei, J Zhang, Q Hu, W Hu, M Cao… - Journal of translational …, 2022 - Springer
Background To construct a predictive model of immunotherapy efficacy for patients with lung
squamous cell carcinoma (LUSC) based on the degree of tumor-infiltrating immune cells …

Exploring scavenger receptor class F member 2 and the importance of scavenger receptor family in prediagnostic diseases

TTT Vo, G Kong, C Kim, U Juang, S Gwon, W Jung… - Toxicological …, 2023 - Springer
Abstract Scavenger Receptor Class F Member 2 (SCARF2), also known as the Type F
Scavenger Receptor Family gene, encodes for Scavenger Receptor Expressed by …

[HTML][HTML] Eleven inflammation-related genes risk signature model predicts prognosis of patients with breast cancer

H Hu, S Yuan, Y Fu, H Li, S Xiao, Z Gong… - Translational Cancer …, 2024 - ncbi.nlm.nih.gov
Background Changes in gene expression are associated with malignancy. Analysis of gene
expression data could be used to reveal cancer subtypes, key molecular drivers, and …

Establishment of a prognostic model for pancreatic cancer based on vesicle-mediated transport protein-related genes

Y Cao, R Xing, F Yang, Y Zhang… - Computer Methods in …, 2024 - Taylor & Francis
This study attempted to build a prognostic riskscore model for pancreatic cancer (PC)
patients based on vesicle-mediated transport protein-related genes (VMTGs). We initially …

Structure of scavenger receptor SCARF1 and its interaction with lipoproteins

Y Wang, F Xu, G Li, C Cheng, B Yu, Z Zhang, D Kong… - bioRxiv, 2023 - biorxiv.org
SCARF1 (Scavenger receptor class F member 1, SREC-1 or SR-F1) is a type I
transmembrane protein that recognizes multiple endogenous and exogenous ligands such …

[PDF][PDF] Scavenger Receptors: Novel Roles in the Pathogenesis of Liver Inflammation and Cancer

S Shetty - 2021 - researchgate.net
Liver disease is one of the leading causes of mortality in the United Kingdom, with cirrhosis
becoming one of the top three causes of premature death in people aged 30 to 60 years. 1 …

Exploring the prognostic value of SCARF1 in non-small cell lung cancers

DA Patten, S Shetty - bioRxiv, 2021 - biorxiv.org
Scavenger receptor class F member 1 (SCARF1) has previously been shown to be highly
expressed within the human liver, hold prognostic value in hepatocellular carcinoma and …