Extrapolating brain development from experimental species to humans
To better understand the neurotoxic effects of diverse hazards on the developing human
nervous system, researchers and clinicians rely on data collected from a number of model …
nervous system, researchers and clinicians rely on data collected from a number of model …
The clockwork embryo: mechanisms regulating developmental rate
M Diaz-Cuadros, O Pourquié - Annual Review of Genetics, 2023 - annualreviews.org
Organismal development requires the reproducible unfolding of an ordered sequence of
discrete steps (cell fate determination, migration, tissue folding, etc.) in both time and space …
discrete steps (cell fate determination, migration, tissue folding, etc.) in both time and space …
Gene expression across mammalian organ development
M Cardoso-Moreira, J Halbert, D Valloton, B Velten… - Nature, 2019 - nature.com
The evolution of gene expression in mammalian organ development remains largely
uncharacterized. Here we report the transcriptomes of seven organs (cerebrum, cerebellum …
uncharacterized. Here we report the transcriptomes of seven organs (cerebrum, cerebellum …
[HTML][HTML] A stem cell zoo uncovers intracellular scaling of developmental tempo across mammals
J Lázaro, M Costanzo, M Sanaki-Matsumiya, C Girardot… - Cell Stem Cell, 2023 - cell.com
Differential speeds in biochemical reactions have been proposed to be responsible for the
differences in developmental tempo between mice and humans. However, the underlying …
differences in developmental tempo between mice and humans. However, the underlying …
Developmental stages in human embryos: revised and new measurements
R O'rahilly, F Müller - Cells Tissues Organs, 2010 - karger.com
The staging of human embryos, as distinct from seriation, depends on a morphological
scheme devised by Streeter and completed by O'Rahilly, who proposed the term Carnegie …
scheme devised by Streeter and completed by O'Rahilly, who proposed the term Carnegie …
An interactive three-dimensional digital atlas and quantitative database of human development
BS de Bakker, KH de Jong, J Hagoort, K de Bree… - Science, 2016 - science.org
INTRODUCTION The basic human body plan, the arrangement of organs in the body, is laid
down during embryonic development. Insight into the formation of this plan informs …
down during embryonic development. Insight into the formation of this plan informs …
[HTML][HTML] Novel findings from CNVs implicate inhibitory and excitatory signaling complexes in schizophrenia
We sought to obtain novel insights into schizophrenia pathogenesis by exploiting the
association between the disorder and chromosomal copy number (CNV) burden. We …
association between the disorder and chromosomal copy number (CNV) burden. We …
FoxP2 expression in avian vocal learners and non-learners
S Haesler, K Wada, A Nshdejan… - Journal of …, 2004 - Soc Neuroscience
Most vertebrates communicate acoustically, but few, among them humans, dolphins and
whales, bats, and three orders of birds, learn this trait. FOXP2 is the first gene linked to …
whales, bats, and three orders of birds, learn this trait. FOXP2 is the first gene linked to …
Dissecting human embryonic skeletal stem cell ontogeny by single-cell transcriptomic and functional analyses
J He, J Yan, J Wang, L Zhao, Q Xin, Y Zeng, Y Sun… - Cell research, 2021 - nature.com
Human skeletal stem cells (SSCs) have been discovered in fetal and adult long bones.
However, the spatiotemporal ontogeny of human embryonic SSCs during early …
However, the spatiotemporal ontogeny of human embryonic SSCs during early …
[图书][B] The embryonic human brain: an atlas of developmental stages
RR O'Rahilly, M Fabiola - 2006 - books.google.com
The new edition of The Embryonic Human Brain: An Atlas of Developmental Stages
represents the integration of analysis of the serial sections of human embryos in the …
represents the integration of analysis of the serial sections of human embryos in the …