Extrapolating brain development from experimental species to humans

B Clancy, BL Finlay, RB Darlington, KJS Anand - Neurotoxicology, 2007 - Elsevier
To better understand the neurotoxic effects of diverse hazards on the developing human
nervous system, researchers and clinicians rely on data collected from a number of model …

The clockwork embryo: mechanisms regulating developmental rate

M Diaz-Cuadros, O Pourquié - Annual Review of Genetics, 2023 - annualreviews.org
Organismal development requires the reproducible unfolding of an ordered sequence of
discrete steps (cell fate determination, migration, tissue folding, etc.) in both time and space …

Gene expression across mammalian organ development

M Cardoso-Moreira, J Halbert, D Valloton, B Velten… - Nature, 2019 - nature.com
The evolution of gene expression in mammalian organ development remains largely
uncharacterized. Here we report the transcriptomes of seven organs (cerebrum, cerebellum …

[HTML][HTML] A stem cell zoo uncovers intracellular scaling of developmental tempo across mammals

J Lázaro, M Costanzo, M Sanaki-Matsumiya, C Girardot… - Cell Stem Cell, 2023 - cell.com
Differential speeds in biochemical reactions have been proposed to be responsible for the
differences in developmental tempo between mice and humans. However, the underlying …

Developmental stages in human embryos: revised and new measurements

R O'rahilly, F Müller - Cells Tissues Organs, 2010 - karger.com
The staging of human embryos, as distinct from seriation, depends on a morphological
scheme devised by Streeter and completed by O'Rahilly, who proposed the term Carnegie …

An interactive three-dimensional digital atlas and quantitative database of human development

BS de Bakker, KH de Jong, J Hagoort, K de Bree… - Science, 2016 - science.org
INTRODUCTION The basic human body plan, the arrangement of organs in the body, is laid
down during embryonic development. Insight into the formation of this plan informs …

[HTML][HTML] Novel findings from CNVs implicate inhibitory and excitatory signaling complexes in schizophrenia

AJ Pocklington, E Rees, JTR Walters, J Han… - Neuron, 2015 - cell.com
We sought to obtain novel insights into schizophrenia pathogenesis by exploiting the
association between the disorder and chromosomal copy number (CNV) burden. We …

FoxP2 expression in avian vocal learners and non-learners

S Haesler, K Wada, A Nshdejan… - Journal of …, 2004 - Soc Neuroscience
Most vertebrates communicate acoustically, but few, among them humans, dolphins and
whales, bats, and three orders of birds, learn this trait. FOXP2 is the first gene linked to …

Dissecting human embryonic skeletal stem cell ontogeny by single-cell transcriptomic and functional analyses

J He, J Yan, J Wang, L Zhao, Q Xin, Y Zeng, Y Sun… - Cell research, 2021 - nature.com
Human skeletal stem cells (SSCs) have been discovered in fetal and adult long bones.
However, the spatiotemporal ontogeny of human embryonic SSCs during early …

[图书][B] The embryonic human brain: an atlas of developmental stages

RR O'Rahilly, M Fabiola - 2006 - books.google.com
The new edition of The Embryonic Human Brain: An Atlas of Developmental Stages
represents the integration of analysis of the serial sections of human embryos in the …