Smart nanomaterials in cancer theranostics: challenges and opportunities
Cancer is ranked as the second leading cause of death globally. Traditional cancer
therapies including chemotherapy are flawed, with off-target and on-target toxicities on the …
therapies including chemotherapy are flawed, with off-target and on-target toxicities on the …
A review of nanotechnology-based approaches for breast cancer and triple-negative breast cancer
Breast cancer (BC) is one of the most prevalent cancers in women. Triple-negative breast
cancer (TNBC) in which the three major receptors ie estrogen receptor (ER), progesterone …
cancer (TNBC) in which the three major receptors ie estrogen receptor (ER), progesterone …
Stem cell–homing hydrogel-based miR-29b-5p delivery promotes cartilage regeneration by suppressing senescence in an osteoarthritis rat model
J Zhu, S Yang, Y Qi, Z Gong, H Zhang, K Liang… - Science …, 2022 - science.org
Osteoarthritis (OA) is a common joint disease characterized by progressive loss of cartilage
and reduction in lubricating synovial fluid, which lacks effective treatments currently. Here …
and reduction in lubricating synovial fluid, which lacks effective treatments currently. Here …
Rolling circle replication for biosensing, bioimaging, and biomedicine
S Yue, Y Li, Z Qiao, W Song, S Bi - Trends in Biotechnology, 2021 - cell.com
Rolling circle replication (RCR), including rolling circle amplification (RCA) and rolling circle
transcription (RCT), is an isothermal enzymatic reaction. Because of its high amplification …
transcription (RCT), is an isothermal enzymatic reaction. Because of its high amplification …
Smart nanovesicle-mediated immunogenic cell death through tumor microenvironment modulation for effective photodynamic immunotherapy
Combination therapy that could better balance immune activation and suppressive signals
holds great potential in cancer immunotherapy. Herein, we serendipitously found that the pH …
holds great potential in cancer immunotherapy. Herein, we serendipitously found that the pH …
DNA nanostructure-based nucleic acid probes: construction and biological applications
DX Wang, J Wang, YX Wang, YC Du, Y Huang… - Chemical …, 2021 - pubs.rsc.org
In recent years, DNA has been widely noted as a kind of material that can be used to
construct building blocks for biosensing, in vivo imaging, drug development, and disease …
construct building blocks for biosensing, in vivo imaging, drug development, and disease …
[HTML][HTML] Drug resistance in metastatic breast cancer: tumor targeted nanomedicine to the rescue
Breast cancer, specifically metastatic breast, is a leading cause of morbidity and mortality in
women. This is mainly due to relapse and reoccurrence of tumor. The primary reason for …
women. This is mainly due to relapse and reoccurrence of tumor. The primary reason for …
Functional DNA–polymer conjugates
CJ Whitfield, M Zhang, P Winterwerber, Y Wu… - Chemical …, 2021 - ACS Publications
DNA nanotechnology has seen large developments over the last 30 years through the
combination of solid phase synthesis and the discovery of DNA nanostructures. Solid phase …
combination of solid phase synthesis and the discovery of DNA nanostructures. Solid phase …
Transformable ECM deprivation system effectively suppresses renal cell carcinoma by reversing anoikis resistance and increasing chemotherapy sensitivity
L Wang, C Li, J Wang, G Yang, Y Lv, B Fu… - Advanced …, 2022 - Wiley Online Library
Extracellular matrix (ECM) is crucial in various biological functions during tumor progression,
including induction of anoikis resistance and cell adhesion‐mediated drug resistance (CAM …
including induction of anoikis resistance and cell adhesion‐mediated drug resistance (CAM …
Hydrophobic interaction: a promising driving force for the biomedical applications of nucleic acids
The comprehensive understanding and proper use of supramolecular interactions have
become critical for the development of functional materials, and so is the biomedical …
become critical for the development of functional materials, and so is the biomedical …