Polyphenols in health and disease: gut microbiota, bioaccessibility, and bioavailability

J Bié, B Sepodes, PCB Fernandes, MHL Ribeiro - Compounds, 2023 - mdpi.com
Polyphenolic compounds (PC) are among the most abundant secondary metabolites in
nature. They are widely distributed in the world and can be found in fruits, cereals, tea …

A Review of the changes produced by extrusion cooking on the bioactive compounds from vegetal sources

S Mironeasa, I Coţovanu, C Mironeasa… - Antioxidants, 2023 - mdpi.com
The demand for healthy ready-to-eat foods like snacks is increasing. Physical modification of
vegetal food matrices through extrusion generates significant changes in the chemical …

Defining the Role of Isoeugenol from Ocimum tenuiflorum against Diabetes Mellitus-Linked Alzheimer's Disease through Network Pharmacology and Computational …

RM Martiz, SM Patil, M Abdulaziz, A Babalghith… - Molecules, 2022 - mdpi.com
The present study involves the integrated network pharmacology and phytoinformatics-
based investigation of phytocompounds from Ocimum tenuiflorum against diabetes mellitus …

Discovery of novel coumarin derivatives as potential dual inhibitors against α-glucosidase and α-amylase for the management of post-prandial hyperglycemia via …

SM Patil, RM Martiz, AM Satish, AM Shbeer, M Ageel… - Molecules, 2022 - mdpi.com
Coumarin derivatives are proven for their therapeutic uses in several human diseases and
disorders such as inflammation, neurodegenerative disorders, cancer, fertility, and microbial …

Computer-Aided Screening of Phytoconstituents from Ocimum tenuiflorum against Diabetes Mellitus Targeting DPP4 Inhibition: A Combination of Molecular Docking …

H Sajal, SM Patil, R Raj, AM Shbeer, M Ageel, R Ramu - Molecules, 2022 - mdpi.com
Diabetes mellitus is a major global health concern in the current scenario which is chiefly
characterized by the rise in blood sugar levels or hyperglycemia. In the context, DPP4 …

Integrated network pharmacology and molecular modeling approach for the discovery of novel potential MAPK3 inhibitors from whole green jackfruit flour targeting …

T Maradesha, RM Martiz, SM Patil, A Prasad… - Plos one, 2023 - journals.plos.org
The current study investigates the effectiveness of phytocompounds from the whole green
jackfruit flour methanol extract (JME) against obesity-linked diabetes mellitus using …

[HTML][HTML] Pharmacoinformatics based screening discovers swertianolin from Lavandula angustifolia as a novel neuromodulator targeting epilepsy, depression, and …

SM Patil, KA Al-Mutairi, N Firdose, R Ramu… - South African Journal of …, 2022 - Elsevier
In the present study, we evaluate the pharmacological significance of phytoconstituents
derived from Lavandula angustifolia with respect to anticonvulsant, antidepressant, and …

Understanding the digestibility of wheat starch-caffeic acid complexes prepared by hot-extrusion 3D printing technology

XR Cui, YS Wang, Y Chen, HY Mu, HH Chen - Food Hydrocolloids, 2023 - Elsevier
In this study, WS-CA complexes were prepared with wheat starch (WS) and caffeic acid (CA)
by the hot-extrusion 3D printing (HE-3DP) technology. In vitro digestion experiment was …

Phyto-Computational Intervention of Diabetes Mellitus at Multiple Stages Using Isoeugenol from Ocimum tenuiflorum: A Combination of Pharmacokinetics and …

RM Martiz, SM Patil, D Thirumalapura Hombegowda… - Molecules, 2022 - mdpi.com
In the present study, the anti-diabetic potential of Ocimum tenuiflorum was investigated
using computational techniques for α-glucosidase, α-amylase, aldose reductase, and …

Molecular insights into the in silico discovery of corilagin from Terminalia chebula as a potential dual inhibitor of SARS-CoV-2 structural proteins

S Pradeep, SM Patil, C Dharmashekara… - Journal of …, 2023 - Taylor & Francis
The spike (S) glycoprotein and nucleocapsid (N) proteins are the crucial pathogenic proteins
of the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS CoV-2) virus during its …