Recent advances in Alzheimer's disease: Mechanisms, clinical trials and new drug development strategies

J Zhang, Y Zhang, J Wang, Y Xia, J Zhang… - Signal transduction and …, 2024 - nature.com
Alzheimer's disease (AD) stands as the predominant form of dementia, presenting significant
and escalating global challenges. Its etiology is intricate and diverse, stemming from a …

Effects of COVID-19 on cognition and brain health

S Zhao, S Toniolo, A Hampshire, M Husain - Trends in cognitive sciences, 2023 - cell.com
COVID-19 is associated with a range of neurological, cognitive, and mental health
symptoms both acutely and chronically that can persist for many months after infection in …

[HTML][HTML] COVID-19 rebound after Paxlovid and Molnupiravir during January-June 2022

L Wang, NA Berger, PB Davis, DC Kaelber, ND Volkow… - MedRxiv, 2022 - ncbi.nlm.nih.gov
COVID-19 rebound after Paxlovid and Molnupiravir during January-June 2022 - PMC Back
to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI …

Increased risk for COVID‐19 breakthrough infection in fully vaccinated patients with substance use disorders in the United States between December 2020 and …

L Wang, QQ Wang, PB Davis, ND Volkow… - World …, 2022 - Wiley Online Library
Individuals with substance use disorders (SUDs) are at increased risk for COVID‐19
infection and for adverse outcomes of the infection. Though vaccines are highly effective …

Association of COVID-19 with new-onset Alzheimer's disease

L Wang, PB Davis, ND Volkow… - Journal of …, 2022 - content.iospress.com
An infectious etiology of Alzheimer's disease has been postulated for decades. It remains
unknown whether SARS-CoV-2 viral infection is associated with increased risk for …

Mental and neurological disorders and risk of COVID-19 susceptibility, illness severity and mortality: a systematic review, meta-analysis and call for action

L Liu, SY Ni, W Yan, QD Lu, YM Zhao, YY Xu… - …, 2021 - thelancet.com
Abstract Background Coronavirus disease 2019 (COVID-19) has evolved into a worldwide
pandemic, and has been found to be closely associated with mental and neurological …

Network medicine links SARS-CoV-2/COVID-19 infection to brain microvascular injury and neuroinflammation in dementia-like cognitive impairment

Y Zhou, J Xu, Y Hou, JB Leverenz, A Kallianpur… - Alzheimer's research & …, 2021 - Springer
Background Dementia-like cognitive impairment is an increasingly reported complication of
SARS-CoV-2 infection. However, the underlying mechanisms responsible for this …

COVID-19 breakthrough infections, hospitalizations and mortality in fully vaccinated patients with hematologic malignancies: a clarion call for maintaining mitigation …

L Wang, DC Kaelber, R Xu, NA Berger - Blood reviews, 2022 - Elsevier
There has been limited data presented to characterize and quantify breakthrough SARS-
CoV-2 infections, hospitalizations, and mortality in vaccinated patients with hematologic …

The COVID-19 pandemic and Alzheimer's disease: mutual risks and mechanisms

F Chen, Y Chen, Y Wang, Q Ke, L Cui - Translational neurodegeneration, 2022 - Springer
Abstract Coronavirus disease 2019 (COVID-19), which is caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), is a life-threatening disease, especially …

KG-Predict: A knowledge graph computational framework for drug repurposing

Z Gao, P Ding, R Xu - Journal of biomedical informatics, 2022 - Elsevier
The emergence of large-scale phenotypic, genetic, and other multi-model biochemical data
has offered unprecedented opportunities for drug discovery including drug repurposing …