Proton MRS (1H MRS) provides noninvasive, quantitative metabolite profiles of tissue and
has been shown to aid the clinical management of several brain diseases. Although most …

The development of magnetic resonance imaging (MRI) for use in medical investigation has
provided a huge forward leap in the field of diagnosis, particularly with avoidance of …

Once an MRS dataset has been acquired, several important steps must be taken to obtain
the desired metabolite concentration measures. First, the data must be preprocessed to …

There is growing interest in the therapeutic utility of psychedelic substances, like psilocybin,
for disorders characterized by distortions of the self-experience, like depression …

Despite the fact that MRI has evolved to become the standard method for diagnosis and
monitoring of patients with brain tumours, conventional MRI sequences have two key …

A large body of published work shows that proton (hydrogen 1 [1H]) magnetic resonance
(MR) spectroscopy has evolved from a research tool into a clinical neuroimaging modality …

In this paper, we analyse two well-known objective image quality metrics, the peak-signal-to-
noise ratio (PSNR) as well as the structural similarity index measure (SSIM), and we derive a …

The current knowledge of the normal biochemistry of compounds that give rise to
resonances in human brain proton magnetic resonance spectra measureable at readily …

Cramér Rao Lower Bounds (CRLB) have become the standard for expression of
uncertainties in quantitative MR spectroscopy. If properly interpreted as a lower threshold of …

Conventional proton MRS has been successfully utilized to noninvasively assess tissue
biochemistry in conditions that result in large changes in metabolite levels. For more …