Pulpal and periapical diseases account for a large proportion of dental visits, the current
treatments for which are root canal therapy (RCT) and pulp revascularisation. Despite the …

Extracellular vesicles (EVs) are biological nanoparticles naturally secreted by cells, acting
as delivery vehicles for molecular messages. During the last decade, EVs have been …

In clinical practice, repairing osteochondral defects presents a challenge due to the varying
biological properties of articular cartilages and subchondral bones. Thus, elucidating how …

Mesenchymal stem cells (MSCs) are the most frequently used stem cells in clinical trials due
to their easy isolation from various adult tissues, their ability of homing to injury sites and …

Direct implantation of mesenchymal stem cells (MSCs) for cartilage and bone tissue
engineering faces challenges, such as immune rejection and loss of cellular viability or …

Mesenchymal stem cell (MSC) derived extracellular vesicles (EVs) in their naïve and
engineered forms have emerged as potential alternatives to stem cell therapy. While they …

Chronic diabetic wounds are primarily caused by infection, inflammation, and angiogenesis-
related disorders. An ideal approach for treating chronic diabetic wounds is by combining …

Background Exosomes derived from dental pulp stem cells (DPSCs) can be used as
biomimetic tools to induce odontogenic differentiation of stem cells, but the regulatory …

Milk consumption is a hallmark of western diet. According to common believes, milk
consumption has beneficial effects for human health. Pasteurization of cow's milk protects …

Stem cell–derived extracellular vesicles (EVs) offer alternative approaches to stem cell–
based therapy for regenerative medicine. In this study, stem cell EVs derived during …