Phenolic compounds as Nrf2 inhibitors: potential applications in cancer therapy

J Sharifi-Rad, V Seidel, M Izabela… - Cell Communication and …, 2023 - Springer
Cancer is a leading cause of death worldwide and involves an oxidative stress mechanism.
The transcription factor Nrf2 has a crucial role in cytoprotective response against oxidative …

Role of reactive oxygen species in myelodysplastic syndromes

Q Jing, C Zhou, J Zhang, P Zhang, Y Wu, J Zhou… - Cellular & Molecular …, 2024 - Springer
Reactive oxygen species (ROS) serve as typical metabolic byproducts of aerobic life and
play a pivotal role in redox reactions and signal transduction pathways. Contingent upon …

Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma

P Kubatka, M Kello, K Kajo, M Samec… - International journal of …, 2020 - mdpi.com
Comprehensive scientific data provide evidence that isolated phytochemicals or whole plant
foods may beneficially modify carcinogenesis. The aim of this study was to evaluate the …

Urtica dioica Leaf Infusion Enhances the Sensitivity of Triple-Negative Breast Cancer Cells to Cisplatin Treatment

G Nafeh, M Abi Akl, J Samarani, R Bahous, G Al Kari… - Pharmaceuticals, 2023 - mdpi.com
Urtica dioica (UD) has been widely used in traditional medicine due to its therapeutic
benefits, including its anticancer effects. Natural compounds have a promising potential …

[HTML][HTML] The pro-apoptotic properties of a phytonutrient rich infusion of A. cherimola leaf extract on AML cells

T Haykal, M Younes, M El Khoury, C Ammoury… - Biomedicine & …, 2021 - Elsevier
Annonaceae family has broad uses in herbal medicine for treatment of several diseases,
whether through seeds' or leaves' extracts. The present study investigates the …

Comprehensive review of Urtica dioica L. (Urticaceae) phytochemistry and anti-inflammatory properties

R Parente, AC Paiva-Santos, C Cabral, G Costa - Phytochemistry Reviews, 2024 - Springer
Herbal medicinal products are widely considered beneficial and gaining importance in
preventing and treating several diseases. Urtica dioica L.(UD) is a medicinal plant that has …

Antitumor efficacy of Urtica sp. leaves extract: in vitro and in vivo studies

RSED Fakher El Deen, SA El-Naggar… - Journal of Bioscience …, 2022 - journals.ekb.eg
Background: Natural products demonstrated potential for use in medicine and
pharmaceuticals. Objective: This study evaluated the phytochemical composition of Urtica …

Application of a direct immersion—Stir bar sorptive extraction (DI-SBSE) combined GC–MS method for fingerprinting alkylpyrazines in tea and tea-like infusions

M Rigling, JP Kanter, Y Zhang - European Food Research and …, 2022 - Springer
A series of alkylpyrazines, contributing to the overall flavor, are described in tea and tea
infusions. Their low concentrations and moderate water solubility are facing analytical …

[HTML][HTML] Healing capacities of nettles: Dendrocnide, Girardinia, Laportea, and Urtica

WD Gunardi, SE Sudradjat, KH Timotius - Phytomedicine Plus, 2023 - Elsevier
Abstract Introduction Dendrocnide, Girardinia, Laportea, and Urtica are members of the
stinging nettle family (Urticaceae) that have fine stinging needles on their aerial parts …

The Agglutinin of Common Nettle (Urtica dioica L.) Plant Effects on Gene Expression Related to Apoptosis of Human Acute Myeloid Leukemia Cell Line

A Rashidbaghan, A Mostafaie, Y Yazdani… - Biochemical …, 2021 - Springer
Abstract Treatment of acute myeloid leukemia (AML) requires new drugs as result of a rise in
new cases and high disease relapse. Plant lectins with the ability to bind carbohydrates on …