Intracellular delivery is a key step in biological research and has enabled decades of
biomedical discoveries. It is also becoming increasingly important in industrial and medical …

Blood-brain barrier (BBB) remains a significant obstacle to drug therapy for brain diseases.
Focused ultrasound (FUS) combined with microbubbles (MBs) can locally and transiently …

In the past two decades, research has underlined the potential of ultrasound and
microbubbles to enhance drug delivery. However, there is less consensus on the …

The past several decades have witnessed great progress in “smart drug delivery”, an
advance technology that can deliver genes or drugs into specific locations of patients' body …

Sonoporation, or the use of ultrasound in the presence of cavitation nuclei to induce plasma
membrane perforation, is well considered as an emerging physical approach to facilitate the …

Ultrasound-driven microbubbles can trigger reversible membrane perforation
(sonoporation), open interendothelial junctions and stimulate endocytosis, thereby providing …

Microbubbles are increasingly being used in biomedical applications such as ultrasonic
imaging and targeted drug delivery. Microbubbles typically range from 0.1 to 10 µm in size …

Introduction: Ultrasound in combination with microbubbles can make cells and tissues more
accessible for drugs, thereby achieving improved therapeutic outcomes. In this review, we …

Broadly speaking, acoustic streaming is generated by a nonlinear acoustic wave with a finite
amplitude propagating in a viscid fluid. The fluid volume elements of molecules, d V, are …

Doxorubicin (DOX) is a potent chemotherapy drug that is often limited by severe adverse
effects such as cardiac toxicity and myelosupression. Drug targeting with non invasive …