Rewiring cellular networks by members of the Flaviviridae family
CJ Neufeldt, M Cortese, EG Acosta… - Nature Reviews …, 2018 - nature.com
Members of the Flaviviridae virus family comprise a large group of enveloped viruses with a
single-strand RNA genome of positive polarity. Several genera belong to this family …
single-strand RNA genome of positive polarity. Several genera belong to this family …
Zika virus: History, emergence, biology, and prospects for control
Zika virus (ZIKV), a previously obscure flavivirus closely related to dengue, West Nile,
Japanese encephalitis and yellow fever viruses, has emerged explosively since 2007 to …
Japanese encephalitis and yellow fever viruses, has emerged explosively since 2007 to …
A screen of FDA-approved drugs for inhibitors of Zika virus infection
NJ Barrows, RK Campos, ST Powell, KR Prasanth… - Cell host & …, 2016 - cell.com
Currently there are no approved vaccines or specific therapies to prevent or treat Zika virus
(ZIKV) infection. We interrogated a library of FDA-approved drugs for their ability to block …
(ZIKV) infection. We interrogated a library of FDA-approved drugs for their ability to block …
N6-methyladenosine in flaviviridae viral RNA genomes regulates infection
The RNA modification N6-methyladenosine (m 6 A) post-transcriptionally regulates RNA
function. The cellular machinery that controls m 6 A includes methyltransferases and …
function. The cellular machinery that controls m 6 A includes methyltransferases and …
Biochemistry and molecular biology of flaviviruses
Flaviviruses, such as dengue, Japanese encephalitis, tick-borne encephalitis, West Nile,
yellow fever, and Zika viruses, are critically important human pathogens that sicken a …
yellow fever, and Zika viruses, are critically important human pathogens that sicken a …
[HTML][HTML] Identification of Zika virus and dengue virus dependency factors using functional genomics
G Savidis, WM McDougall, P Meraner, JM Perreira… - Cell reports, 2016 - cell.com
The flaviviruses dengue virus (DENV) and Zika virus (ZIKV) are severe health threats with
rapidly expanding ranges. To identify the host cell dependencies of DENV and ZIKV, we …
rapidly expanding ranges. To identify the host cell dependencies of DENV and ZIKV, we …
Envelope protein ubiquitination drives entry and pathogenesis of Zika virus
Zika virus (ZIKV) belongs to the family Flaviviridae, and is related to other viruses that cause
human diseases. Unlike other flaviviruses, ZIKV infection can cause congenital neurological …
human diseases. Unlike other flaviviruses, ZIKV infection can cause congenital neurological …
Structures and functions of the envelope glycoprotein in flavivirus infections
X Zhang, R Jia, H Shen, M Wang, Z Yin, A Cheng - Viruses, 2017 - mdpi.com
Flaviviruses are enveloped, single-stranded RNA viruses that widely infect many animal
species. The envelope protein, a structural protein of flavivirus, plays an important role in …
species. The envelope protein, a structural protein of flavivirus, plays an important role in …
Yellow fever virus: knowledge gaps impeding the fight against an old foe
Yellow fever (YF) was one of the most dangerous infectious diseases of the 18th and 19th
centuries, resulting in mass casualties in Africa and the Americas. The etiologic agent is …
centuries, resulting in mass casualties in Africa and the Americas. The etiologic agent is …
Single-cell transcriptional dynamics of flavivirus infection
Dengue and Zika viral infections affect millions of people annually and can be complicated
by hemorrhage and shock or neurological manifestations, respectively. However, a thorough …
by hemorrhage and shock or neurological manifestations, respectively. However, a thorough …