Lactic acid bacteria in raw-milk cheeses: From starter cultures to probiotic functions

MC Coelho, FX Malcata, CCG Silva - Foods, 2022 - mdpi.com
Traditional cheeses produced from raw milk exhibit a complex microbiota, characterized by
a sequence of different microorganisms from milk coagulation and throughout maturation …

Mesenchymal stromal cells for improvement of cardiac function following acute myocardial infarction: a matter of timing

S Barrère-Lemaire, A Vincent… - Physiological …, 2024 - journals.physiology.org
Acute myocardial infarction (AMI) is the leading cause of cardiovascular death and remains
the most common cause of heart failure. Reopening of the occluded artery, ie, reperfusion, is …

Distinct properties of adipose stem cell subpopulations determine fat depot-specific characteristics

H Nahmgoong, YG Jeon, ES Park, YH Choi, SM Han… - Cell metabolism, 2022 - cell.com
In mammals, white adipose tissues are largely divided into visceral epididymal adipose
tissue (EAT) and subcutaneous inguinal adipose tissue (IAT) with distinct metabolic …

Exosomes from adipose-derived stem cells alleviate the inflammation and oxidative stress via regulating Nrf2/HO-1 axis in macrophages

K Shen, Y Jia, X Wang, J Zhang, K Liu, J Wang… - Free Radical Biology …, 2021 - Elsevier
ADSCs exosomes, an important means of intercellular communication, can regulate an
array of biological processes, including promoting tissue repairs and regeneration, and …

[HTML][HTML] SREBP1c-PARP1 axis tunes anti-senescence activity of adipocytes and ameliorates metabolic imbalance in obesity

G Lee, YY Kim, H Jang, JS Han, H Nahmgoong… - Cell metabolism, 2022 - cell.com
Emerging evidence indicates that the accretion of senescent cells is linked to metabolic
disorders. However, the underlying mechanisms and metabolic consequences of cellular …

GABA transporter sustains IL-1β production in macrophages

Y Xia, F He, X Wu, B Tan, S Chen, Y Liao, M Qi… - Science …, 2021 - science.org
Accumulating evidence shows that nervous system governs host immune responses;
however, how γ-aminobutyric acid (GABA) ergic system shapes the function of innate …

Inhibiting serotonin signaling through HTR2B in visceral adipose tissue improves obesity-related insulin resistance

WG Choi, W Choi, TJ Oh, HN Cha… - The Journal of …, 2021 - Am Soc Clin Investig
Insulin resistance is a cornerstone of obesity-related complications such as type 2 diabetes,
metabolic syndrome, and nonalcoholic fatty liver disease. A high rate of lipolysis is known to …

Gamma-aminobutyric acid signaling in damage response, metabolism, and disease

K Kim, H Yoon - International Journal of Molecular Sciences, 2023 - mdpi.com
Gamma-aminobutyric acid (GABA) plays a crucial role in signal transduction and can
function as a neurotransmitter. Although many studies have been conducted on GABA in …

Exosome-shuttled miR-150–5p from LPS-preconditioned mesenchymal stem cells down-regulate PI3K/Akt/mTOR pathway via Irs1 to enhance M2 macrophage …

T Zheng, S Li, T Zhang, W Fu, S Liu, Y He… - Frontiers in …, 2024 - frontiersin.org
Rationale Sepsis is a life-threatening organ dysfunction and lack of effective measures in the
current. Exosomes from mesenchymal stem cells (MSCs) reported to alleviate inflammation …

GABA and fermented litchi juice enriched with GABA promote the beneficial effects in ameliorating obesity by regulating the gut microbiota in HFD-induced mice

D Wang, Y Deng, L Zhao, K Wang, D Wu, Z Hu… - Food & Function, 2023 - pubs.rsc.org
Gamma-aminobutyric acid (GABA) dietary intervention is considered to have therapeutic
potential against obesity. Microbial enrichment is an effective strategy to naturally and safely …