D-amino acids and D-amino acid-containing peptides: potential disease biomarkers and therapeutic targets?
M Abdulbagi, L Wang, O Siddig, B Di, B Li - Biomolecules, 2021 - mdpi.com
In nature, amino acids are found in two forms, L and D enantiomers, except for glycine which
does not have a chiral center. The change of one form to the other will lead to a change in …
does not have a chiral center. The change of one form to the other will lead to a change in …
Recent trends of capillary electrophoresis‐mass spectrometry in proteomics research
FP Gomes, JR Yates III - Mass spectrometry reviews, 2019 - Wiley Online Library
Progress in proteomics research has led to a demand for powerful analytical tools with high
separation efficiency and sensitivity for confident identification and quantification of proteins …
separation efficiency and sensitivity for confident identification and quantification of proteins …
Analysis of peptide stereochemistry in single cells by capillary electrophoresis–trapped ion mobility spectrometry mass spectrometry
Single cell analysis strives to probe molecular heterogeneity in morphologically similar cell
populations through quantitative or qualitative measurements of genetic, proteomic, or …
populations through quantitative or qualitative measurements of genetic, proteomic, or …
Spontaneous isomerization of long-lived proteins provides a molecular mechanism for the lysosomal failure observed in Alzheimer's disease
TR Lambeth, DL Riggs, LE Talbert, J Tang… - ACS central …, 2019 - ACS Publications
Proteinaceous aggregation is a well-known observable in Alzheimer's disease (AD), but
failure and storage of lysosomal bodies within neurons is equally ubiquitous and actually …
failure and storage of lysosomal bodies within neurons is equally ubiquitous and actually …
Does data-independent acquisition data contain hidden gems? A case study related to Alzheimer's disease
EE Hubbard, LR Heil, GE Merrihew… - Journal of proteome …, 2021 - ACS Publications
One of the potential benefits of using data-independent acquisition (DIA) proteomics
protocols is that information not originally targeted by the study may be present and …
protocols is that information not originally targeted by the study may be present and …
Self-propelled micromotors for naked-eye detection of phenylenediamines isomers
R Maria-Hormigos, B Jurado-Sanchez… - Analytical …, 2018 - ACS Publications
Tubular micromotors composed of a hybrid single-wall carbon nanotube (SW)–Fe2O3 outer
layer and powered by a MnO2 catalyst are used for phenylenediamines isomers detection …
layer and powered by a MnO2 catalyst are used for phenylenediamines isomers detection …
Separation of β-Amyloid Tryptic Peptide Species with Isomerized and Racemized l-Aspartic Residues with Ion Mobility in Structures for Lossless Ion Manipulations
Accumulation of β-amyloid (Aβ) is one of the hallmarks of Alzheimer's disease. The
deposition of β-amyloid plaques is likely to start years in advance of manifestation of clinical …
deposition of β-amyloid plaques is likely to start years in advance of manifestation of clinical …
Recent developments in capillary and microchip electroseparations of peptides (2017–mid 2019)
V Kašička - Electrophoresis, 2020 - Wiley Online Library
The review presents a comprehensive survey of recent developments and applications of
high performance capillary and microchip electroseparation methods (zone electrophoresis …
high performance capillary and microchip electroseparation methods (zone electrophoresis …
Advancing d-amino acid-containing peptide discovery in the metazoan
The discovery of enzyme-derived d-amino acid-containing peptides (DAACPs) that have
physiological importance in the metazoan challenges previous assumptions about the …
physiological importance in the metazoan challenges previous assumptions about the …
Facile preparation of Cu-doped carbon dots for naked-eye discrimination of phenylenediamine isomers and highly sensitive ratiometric fluorescent detection of H2O2
D Zhao, Y Huang, H Ouyang, B Shi, S Li, S Chen… - Talanta, 2022 - Elsevier
Changing a detection analyte into a colored material is a key challenge for visual
discrimination of isomers. In this work, a novel fluorescent probe incorporating Cu-doped …
discrimination of isomers. In this work, a novel fluorescent probe incorporating Cu-doped …