OBJECTIVE. The purpose of this review is to describe trends in microbubble application in
molecular imaging. CONCLUSION. Microbubbles are used for contrast ultrasound imaging …

Ultrasound targeted microbubble destruction has evolved as a promising tool for organ
specific gene and drug delivery. This technique has initially been developed as a method in …

Thrombosis is an extremely critical clinical condition where a clot forms inside a blood
vessel which blocks the blood flow through the cardiovascular system. Previous …

Introduction: Ultrasound enhancement of thrombolysis (sonothrombolysis) is further
potentiated by administration of acoustically active microbubbles, which may be developed …

JAVMA, Vol 234, No. 4, February 15, 2009 Vet Med Today: Reference Point 461 of the
harmonics). 20 The second harmonic component is therefore separated from the …

Ultrasound molecular imaging has been developed in the past two decades with the goal of
non-invasively imaging disease phenotypes on a cellular level not depicted on anatomic …

The localization of microbubbles to a treatment site has been shown to be essential to their
effectiveness in therapeutic applications such as targeted drug delivery and gene therapy. A …

In acute stroke, different sonographic methods can be used to assess structural and
hemodynamic compromise. Structural abnormalities of brain parenchyma such as primary …

BACKGROUND: Microbubbles have improved ultrasonography imaging techniques over the
past 2 decades. Their safety, versatility, and easiness of use have rendered them equal or …

Despite immense potential, ultrasound molecular imaging (UMI) of arterial thrombi remains
very challenging because the high-shear arterial flow limits binding of site-targeted …