The role of noncoding RNAs in Parkinson's disease: biomarkers and associations with pathogenic pathways
MC Kuo, SCH Liu, YF Hsu, RM Wu - Journal of biomedical science, 2021 - Springer
The discovery of various noncoding RNAs (ncRNAs) and their biological implications is a
growing area in cell biology. Increasing evidence has revealed canonical and noncanonical …
growing area in cell biology. Increasing evidence has revealed canonical and noncanonical …
The lncRNAs at X chromosome inactivation center: Not just a matter of sex dosage compensation
C Siniscalchi, A Di Palo, A Russo… - International Journal of …, 2022 - mdpi.com
Non-coding RNAs (ncRNAs) constitute the majority of the transcriptome, as the result of
pervasive transcription of the mammalian genome. Different RNA species, such as lncRNAs …
pervasive transcription of the mammalian genome. Different RNA species, such as lncRNAs …
LncRNA ZNF883-mediated NLRP3 inflammasome activation and epilepsy development involve USP47 upregulation
L Gong, Y Han, R Chen, P Yang, C Zhang - Molecular Neurobiology, 2022 - Springer
The goal of this study was to characterize the mechanisms of long noncoding RNA (lncRNA)
ZNF883 regulating NOD-like receptor 3 (NLRP3) inflammasome activation in epilepsy (EP) …
ZNF883 regulating NOD-like receptor 3 (NLRP3) inflammasome activation in epilepsy (EP) …
Erinacine a prevents lipopolysaccharide-mediated glial cell activation to protect dopaminergic neurons against inflammatory factor-induced cell death in vitro and in …
SL Lee, JY Hsu, TC Chen, CC Huang, TY Wu… - International Journal of …, 2022 - mdpi.com
Hericium erinaceus (HE) is a common edible mushroom consumed in several Asian
countries and considered to be a medicinal mushroom with neuroprotective effects …
countries and considered to be a medicinal mushroom with neuroprotective effects …
LncRNA PVT1 Promotes neuronal cell apoptosis and neuroinflammation by regulating miR-488-3p/FOXD3/SCN2A axis in epilepsy
F Wen, Z Tan, D Huang, Y Jiang, J Xiang - Neurochemical Research, 2023 - Springer
It is vital to understand the mechanism of epilepsy onset and development. Dysregulated
lncRNAs are closely associated with epilepsy. Our work probed the role of lncRNA …
lncRNAs are closely associated with epilepsy. Our work probed the role of lncRNA …
MicroRNAs in the development of resistance to antiseizure drugs and their potential as biomarkers in pharmacoresistant epilepsy
J Bohosova, J Vajcner, P Jabandziev, H Oslejskova… - …, 2021 - Wiley Online Library
Although many new antiseizure drugs have been developed in the past decade,
approximately 30%–40% of patients remain pharmacoresistant. There are no clinical tools …
approximately 30%–40% of patients remain pharmacoresistant. There are no clinical tools …
Epigenetic regulation in epilepsy: A novel mechanism and therapeutic strategy for epilepsy
S Chen, M Huang, D Xu, M Li - Neurochemistry International, 2024 - Elsevier
Epilepsy is a common neurological disorder characterized by recurrent seizures with
excessive and abnormal neuronal discharges. Epileptogenesis is usually involved in …
excessive and abnormal neuronal discharges. Epileptogenesis is usually involved in …
Emerging roles of long non‐coding RNAs in human epilepsy
Genome‐scale biological studies conducted in the post‐genomic era have revealed that two‐
thirds of human genes do not encode proteins. Most functional non‐coding RNA transcripts …
thirds of human genes do not encode proteins. Most functional non‐coding RNA transcripts …
Long non-coding RNA: an underlying bridge linking neuroinflammation and central nervous system diseases
Z Chen, H Wu, M Zhang - Neurochemistry international, 2021 - Elsevier
Central nervous system (CNS) diseases are responsible for a large proportion of morbidity
and mortality worldwide. CNS diseases caused by intrinsic and extrinsic stimuli stimulate the …
and mortality worldwide. CNS diseases caused by intrinsic and extrinsic stimuli stimulate the …
Inhibition of NFAT5‐Dependent Astrocyte Swelling Alleviates Neuropathic Pain
L He, S Ma, Z Ding, Z Huang, Y Zhang, C Xi… - Advanced …, 2024 - Wiley Online Library
Astrocyte swelling is implicated in various neurological disorders. However, whether
astrocyte swelling contributes to neuropathic pain remains elusive. This study elucidates the …
astrocyte swelling contributes to neuropathic pain remains elusive. This study elucidates the …