Atherosclerosis is a chronic inflammatory arterial disease driven by both innate and adaptive
immune responses to modified lipoproteins and components of the injured vascular wall …

Arterial inflammation is a hallmark of atherosclerosis, and appropriate management of this
inflammation represents a major unmet therapeutic need for cardiovascular disease …

Systemic lupus erythematosus (SLE) is a disease characterized by dysregulation and
hyperreactivity of the immune response at various levels, including hyperactivation of …

Despite major advances in prevention and treatment, cardiac and cerebral atherothrombotic
complications still account for substantial morbidity and mortality worldwide. In this context …

Cardiovascular disease is the leading cause of death worldwide, and its prevalence is
increasing due to the aging of societies. Atherosclerosis, a type of chronic inflammatory …

Psoriasis, a chronic immune-mediated disease, is associated with an increased risk of
cardiovascular events and mortality. Secukinumab selectively neutralizes IL-17A and has …

Being a member of the IL-17 family, comprising six structurally related ligands, IL-17A is a
cytokine, produced by multiple cell types, such as CD4+ αβ T cells, γδ T cells, natural killer …

Accumulating observations in humans and animals indicate that inflammation plays a key
role in atherosclerosis development and subsequent complications. Moreover, the use of …

Aims Monocytes are central for atherosclerotic vascular inflammation. The human non-
classical, patrolling subtype, which expresses high levels of CD16 and fractalkine receptor …

Background: Although the role of Th17 and regulatory T cells in the progression of
atherosclerosis has been highlighted in recent years, their molecular mediators remain …