Vitiligo: a review

C Bergqvist, K Ezzedine - Dermatology, 2020 - karger.com
Vitiligo, a common depigmenting skin disorder, has an estimated prevalence of 0.5–2% of
the population worldwide. The disease is characterized by the selective loss of melanocytes …

Vitiligo: a focus on pathogenesis and its therapeutic implications

C Bergqvist, K Ezzedine - The Journal of dermatology, 2021 - Wiley Online Library
Vitiligo is the most common depigmenting disorder affecting 0.1%–2% of the population
worldwide. The characteristic white patches result from the selective loss of melanocytes …

Vitiligo: mechanisms of pathogenesis and treatment

ML Frisoli, K Essien, JE Harris - Annual review of immunology, 2020 - annualreviews.org
Vitiligo is an autoimmune disease of the skin that targets pigment-producing melanocytes
and results in patches of depigmentation that are visible as white spots. Recent research …

Update on the pathogenesis of vitiligo

HZ Marchioro, CCS Castro, VM Fava… - Anais Brasileiros de …, 2022 - SciELO Brasil
Vitiligo is a complex disease whose pathogenesis results from the interaction of genetic
components, metabolic factors linked to cellular oxidative stress, melanocyte adhesion to the …

Vitiligo: focus on clinical aspects, immunopathogenesis, and therapy

K Boniface, J Seneschal, M Picardo, A Taïeb - Clinical reviews in allergy & …, 2018 - Springer
Vitiligo is an acquired chronic depigmenting disorder of the skin, with an estimated
prevalence of 0.5% of the general population, characterized by the development of white …

scRNA-seq of human vitiligo reveals complex networks of subclinical immune activation and a role for CCR5 in Treg function

KJ Gellatly, JP Strassner, K Essien, MA Refat… - Science translational …, 2021 - science.org
Vitiligo is an autoimmune skin disease characterized by the targeted destruction of
melanocytes by T cells. Cytokine signaling between keratinocytes and T cells results in …

Vitiligo: pathogenesis, clinical variants and treatment approaches

G Iannella, A Greco, D Didona, B Didona, G Granata… - Autoimmunity …, 2016 - Elsevier
Vitiligo is a common chronic acquired disease of pigmentation whose etiology is unknown,
which usually occurs with asymptomatic whitish patch or macule. Although several …

[HTML][HTML] Perspectives of new advances in the pathogenesis of vitiligo: from oxidative stress to autoimmunity

Y Wang, S Li, C Li - … medical journal of experimental and clinical …, 2019 - ncbi.nlm.nih.gov
Vitiligo is an autoimmune cutaneous disease in which melanocytes are destroyed by CD8+
T cells resulting in disfiguring white spots. From the very beginning of the disease, oxidative …

Vitiligo: interplay between oxidative stress and immune system

NC Laddha, M Dwivedi, MS Mansuri… - Experimental …, 2013 - Wiley Online Library
Vitiligo is a multifactorial polygenic disorder with a complex pathogenesis, linked with both
genetic and non‐genetic factors. The precise modus operandi for vitiligo pathogenesis has …

Induction of regulatory T cells: a role for probiotics and prebiotics to suppress autoimmunity

M Dwivedi, P Kumar, NC Laddha, EH Kemp - Autoimmunity Reviews, 2016 - Elsevier
Regulatory T cells (Tregs) are comprised of a heterogeneous population of cells that play a
vital role in suppressing inflammation and maintaining immune tolerance. Given the crucial …