Highlights•Enhanced threat processing is a mechanism linking child trauma to
psychopathology.•Information processing biases and altered emotional learning are key …

Current medication for anxiety disorders is suboptimal in terms of efficiency and tolerability,
highlighting the need for improved drug treatments. In this review an overview of drugs …

Background Stressful events due to the coronavirus disease‐2019 (COVID‐19) pandemic
are likely to have profound effects on mental health, and validated methods for assessing …

Objective The strong associations between child maltreatment and psychopathology have
generated interest in identifying neurodevelopmental processes that are disrupted following …

Adolescence is a time in development when significant changes occur in affective
neurobiology. These changes provide a prolonged period of plasticity to prepare the …

Recent neuroimaging studies suggest that the brain adapts with pain, as well as imparts risk
for developing chronic pain. Within this context, we revisit the concepts for nociception, acute …

For more than a century, research on psychopathology has focused on categorical
diagnoses. Although this work has produced major discoveries, growing evidence points to …

Resilience in the face of major life stressors is changeable over time and with experience.
Accordingly, differing sets of neurobiological factors may contribute to an adaptive stress …

Identifying biological mechanisms through which the experience of adversity emerges as
individual risk for mental illness is an important step toward developing strategies for …

Complex posttraumatic stress disorder (CPTSD) has been included as a diagnostic category
in the International Classification of Diseases, 11th Edition, consisting of six symptom …