Data quality aware analysis of differential expression in RNA-seq with NOISeq R/Bioc package
As the use of RNA-seq has popularized, there is an increasing consciousness of the
importance of experimental design, bias removal, accurate quantification and control of false …
importance of experimental design, bias removal, accurate quantification and control of false …
Polyester: simulating RNA-seq datasets with differential transcript expression
Motivation: Statistical methods development for differential expression analysis of RNA
sequencing (RNA-seq) requires software tools to assess accuracy and error rate control …
sequencing (RNA-seq) requires software tools to assess accuracy and error rate control …
Transcriptomics for clinical and experimental biology research: hang on a seq
Sequencing the human genome empowers translational medicine, facilitating transcriptome‐
wide molecular diagnosis, pathway biology, and drug repositioning. Initially, microarrays are …
wide molecular diagnosis, pathway biology, and drug repositioning. Initially, microarrays are …
RNA‐seq reveals regional differences in transcriptome response to heat stress in the marine snail Chlorostoma funebralis
LU Gleason, RS Burton - Molecular ecology, 2015 - Wiley Online Library
To investigate the role of gene expression in adaptation of marine ectotherms to different
temperatures, we examined the transcriptome‐wide thermal stress response in …
temperatures, we examined the transcriptome‐wide thermal stress response in …
Novel mutations associated with combined pituitary hormone deficiency
CJ Romero, E Pine-Twaddell… - Journal of molecular …, 2011 - jme.bioscientifica.com
The pituitary gland produces hormones that play important roles in both the development
and the homeostasis of the body. A deficiency of two or several of these pituitary hormones …
and the homeostasis of the body. A deficiency of two or several of these pituitary hormones …
[HTML][HTML] Enterohemorrhagic Escherichia coli senses microbiota-derived nicotinamide to increase its virulence and colonization in the large intestine
W Yang, H Sun, J Yan, C Kang, J Wu, B Yang - Cell Reports, 2023 - cell.com
Summary Enterohemorrhagic Escherichia coli (EHEC) O157: H7 is a foodborne pathogen
that specifically colonizes and infects the human large intestine. EHEC O157: H7 engages …
that specifically colonizes and infects the human large intestine. EHEC O157: H7 engages …
A comparison of RNA-seq and exon arrays for whole genome transcription profiling of the L5 spinal nerve transection model of neuropathic pain in the rat
Background: The past decade has seen an abundance of transcriptional profiling studies of
preclinical models of persistent pain, predominantly employing microarray technology. In …
preclinical models of persistent pain, predominantly employing microarray technology. In …
Reprogramming of Yersinia from Virulent to Persistent Mode Revealed by Complex In Vivo RNA-seq Analysis
We recently found that Yersinia pseudotuberculosis can be used as a model of persistent
bacterial infections. We performed in vivo RNA-seq of bacteria in small cecal tissue biopsies …
bacterial infections. We performed in vivo RNA-seq of bacteria in small cecal tissue biopsies …
Successful recovery of nuclear protein-coding genes from small insects in museums using Illumina sequencing
K Kanda, JM Pflug, JS Sproul, MA Dasenko… - PLoS …, 2015 - journals.plos.org
In this paper we explore high-throughput Illumina sequencing of nuclear protein-coding,
ribosomal, and mitochondrial genes in small, dried insects stored in natural history …
ribosomal, and mitochondrial genes in small, dried insects stored in natural history …
The functional false discovery rate with applications to genomics
The false discovery rate (FDR) measures the proportion of false discoveries among a set of
hypothesis tests called significant. This quantity is typically estimated based on p-values or …
hypothesis tests called significant. This quantity is typically estimated based on p-values or …