Inflammatory processes that recruit leukocytes to injured or infected tissues are crucial for
tissue repair and the elimination of pathogens. However, excessive or chronic inflammation …

Diseases associated with chronic inflammation constitute a major health burden across the
world. As central instigators of the inflammatory response to infection and tissue damage …

Plasma membrane rupture (PMR) in dying cells undergoing pyroptosis or apoptosis requires
the cell-surface protein NINJ1. PMR releases pro-inflammatory cytoplasmic molecules …

Abstract Ninjurin1 (Ninj1), an adhesion molecule, regulates macrophage function in hyaloid
regression, multiple sclerosis, and atherosclerosis. However, its biological relevance and …

Background & Aims Liver ischemia-reperfusion (IR) injury represents a major risk factor in
both partial hepatectomy and liver transplantation. Nerve injury–induced protein 1 (Ninj1) is …

Background: Macrophages produce many inflammation-associated molecules, released by
matrix metalloproteinases, such as adhesion molecules, and cytokines, as well, which play a …

Pyroptosis, an inflammatory programmed cell death process, has recently garnered
significant attention due to its pivotal role in various neurological diseases. This review …

Activated leukocyte cell adhesion molecule (ALCAM) has been proposed to mediate
leukocyte migration across the blood–brain barrier (BBB) in multiple sclerosis or …

Here we developed a novel green synthesis method for gold nanoparticles (CGA-AuNPs)
using chlorogenic acid (CGA) as reductants without the use of other chemicals and validated …

WT p53 is critical for tumor suppression, whereas mutant p53 promotes tumor progression.
Nerve injury-induced protein 1 (Ninj1) is a target of p53 and forms a feedback loop with p53 …