An overview of the main genetic, epigenetic and environmental factors involved in autism spectrum disorder focusing on synaptic activity
E Masini, E Loi, AF Vega-Benedetti, M Carta… - International journal of …, 2020 - mdpi.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder that affects social
interaction and communication, with restricted interests, activity and behaviors. ASD is highly …
interaction and communication, with restricted interests, activity and behaviors. ASD is highly …
The rationale for vitamin, mineral, and cofactor treatment in the precision medical care of autism spectrum disorder
Children with autism spectrum disorder may exhibit nutritional deficiencies due to reduced
intake, genetic variants, autoantibodies interfering with vitamin transport, and the …
intake, genetic variants, autoantibodies interfering with vitamin transport, and the …
Propionic acid induces alterations in mitochondrial morphology and dynamics in SH-SY5Y cells
Propionic acid (PPA) is used to study the role of mitochondrial dysfunction in
neurodevelopmental conditions like autism spectrum disorders. PPA is known to disrupt …
neurodevelopmental conditions like autism spectrum disorders. PPA is known to disrupt …
Human forebrain organoid-based multi-omics analyses of PCCB as a schizophrenia associated gene linked to GABAergic pathways
W Zhang, M Zhang, Z Xu, H Yan, H Wang… - Nature …, 2023 - nature.com
Identifying genes whose expression is associated with schizophrenia (SCZ) risk by
transcriptome-wide association studies (TWAS) facilitates downstream experimental studies …
transcriptome-wide association studies (TWAS) facilitates downstream experimental studies …
The effectiveness of cobalamin (B12) treatment for autism spectrum disorder: a systematic review and meta-analysis
DA Rossignol, RE Frye - Journal of personalized medicine, 2021 - mdpi.com
Autism spectrum disorder (ASD) is a common neurodevelopmental disorder affecting 2% of
children in the United States. Biochemical abnormalities associated with ASD include …
children in the United States. Biochemical abnormalities associated with ASD include …
An mtDNA mutant mouse demonstrates that mitochondrial deficiency can result in autism endophenotypes
T Yardeni, AG Cristancho, AJ McCoy… - Proceedings of the …, 2021 - National Acad Sciences
Autism spectrum disorders (ASDs) are characterized by a deficit in social communication,
pathologic repetitive behaviors, restricted interests, and electroencephalogram (EEG) …
pathologic repetitive behaviors, restricted interests, and electroencephalogram (EEG) …
The mitochondrial dysfunction hypothesis in autism spectrum disorders: current status and future perspectives
L Citrigno, M Muglia, A Qualtieri, P Spadafora… - International journal of …, 2020 - mdpi.com
Autism spectrum disorders (ASDs) constitute a set of heterogeneous neurodevelopmental
conditions, characterized by a wide genetic variability that has led to hypothesize a …
conditions, characterized by a wide genetic variability that has led to hypothesize a …
Melatonin: Regulation of viral phase separation and Epitranscriptomics in post-acute sequelae of COVID-19
The relentless, protracted evolution of the SARS-CoV-2 virus imposes tremendous pressure
on herd immunity and demands versatile adaptations by the human host genome to counter …
on herd immunity and demands versatile adaptations by the human host genome to counter …
Mitochondrial dysfunction in cognitive neurodevelopmental disorders: Cause or effect?
A Anitha, I Thanseem, M Iype, SV Thomas - Mitochondrion, 2023 - Elsevier
Mitochondria have a crucial role in brain development and neurogenesis, both in embryonic
and adult brains. Since the brain is the highest energy consuming organ, it is highly …
and adult brains. Since the brain is the highest energy consuming organ, it is highly …
Clustered protocadherins emerge as novel susceptibility loci for mental disorders
The clustered protocadherins (cPcdhs) are a subfamily of type I single-pass transmembrane
cell adhesion molecules predominantly expressed in the brain. Their stochastic and …
cell adhesion molecules predominantly expressed in the brain. Their stochastic and …