Class III β‐tubulin in human development and cancer

CD Katsetos, MM Herman… - Cell motility and the …, 2003 - Wiley Online Library
The differential cellular expression of class III β‐tubulin isotype (βIII) is reviewed in the
context of human embryological development and neoplasia. As compared to somatic …

Class III β-tubulin isotype: a key cytoskeletal protein at the crossroads of developmental neurobiology and tumor neuropathology

CD Katsetos, A Legido, E Perentes… - Journal of child …, 2003 - journals.sagepub.com
The expression of the cytoskeletal protein class III β-tubulin isotype is reviewed in the
context of human central nervous system development and neoplasia. Compared to …

Recent advances and current developments in tissue scaffolding

PKDV Yarlagadda… - Bio-medical …, 2005 - content.iospress.com
A bio‐scaffold can be broadly termed as a structure used to substitute an organ either
permanently or temporarily to restore functionality. The material that can be used varies with …

Class III β-tubulin is constitutively coexpressed with glial fibrillary acidic protein and nestin in midgestational human fetal astrocytes: implications for phenotypic identity

E Dráberová, L Del Valle, J Gordon… - … of Neuropathology & …, 2008 - academic.oup.com
Class III β-tubulin isotype (βIII-tubulin) is widely regarded as a neuronal marker in
developmental neurobiology and stem cell research. To test the specificity of this marker …

Human neural stem cells improve cognitive function of aged brain

T Qu, CL Brannen, HM Kim, K Sugaya - Neuroreport, 2001 - journals.lww.com
The capability for in vitro expansion of human neural stem cells (HNSCs) provides a well
characterized and unlimited source alternative to using primary fetal tissue for neuronal …

Polychlorinated biphenyls disturb differentiation of normal human neural progenitor cells: clue for involvement of thyroid hormone receptors

E Fritsche, JE Cline, NH Nguyen… - Environmental health …, 2005 - ehp.niehs.nih.gov
Polychlorinated biphenyls (PCBs) are ubiquitous environmental chemicals that accumulate
in adipose tissues over the food chain. Epidemiologic studies have indicated that PCBs …

Neural progenitor cells as models for high-throughput screens of developmental neurotoxicity: state of the science

JM Breier, K Gassmann, R Kayser, H Stegeman… - Neurotoxicology and …, 2010 - Elsevier
In vitro, high-throughput methods have been widely recommended as an approach to
screen chemicals for the potential to cause developmental neurotoxicity and prioritize them …

Amyloid precursor protein regulates differentiation of human neural stem cells

YD Kwak, CL Brannen, T Qu, HM Kim… - Stem cells and …, 2006 - liebertpub.com
Although amyloid β (Aβ) deposition has been a hallmark of Alzheimer's disease (AD), the
absence of a phenotype in the β amyloid precursor protein (APP) knockout mouse, tends to …

Reelin function in neural stem cell biology

HM Kim, T Qu, V Kriho, P Lacor… - Proceedings of the …, 2002 - National Acad Sciences
In the adult brain, neural stem cells (NSC) must migrate to express their neuroplastic
potential. The addition of recombinant reelin to human NSC (HNSC) cultures facilitates …

Modulation of human neural stem cell differentiation in Alzheimer (APP23) transgenic mice by phenserine

A Marutle, M Ohmitsu, M Nilbratt… - Proceedings of the …, 2007 - National Acad Sciences
In a previous study, we found that human neural stem cells (HNSCs) exposed to high
concentrations of secreted amyloid-precursor protein (sAPP) in vitro differentiated into …