Exploring treatment options in cancer: Tumor treatment strategies

B Liu, H Zhou, L Tan, KTH Siu, XY Guan - Signal Transduction and …, 2024 - nature.com
Traditional therapeutic approaches such as chemotherapy and radiation therapy have
burdened cancer patients with onerous physical and psychological challenges …

Revolutionizing Glioblastoma Treatment: A Comprehensive Overview of Modern Therapeutic Approaches

K Sadowski, A Jażdżewska, J Kozłowski… - International Journal of …, 2024 - mdpi.com
Simple Summary Glioblastoma is one of the most dangerous tumors of the central nervous
system, and still cannot be fully overcome. We still mainly rely on standard treatments …

Glioma–Immune Cell Crosstalk in Tumor Progression

M Elguindy, JS Young, I Mondal, RO Lu, WS Ho - Cancers, 2024 - mdpi.com
Simple Summary The environment surrounding primary glioma brain tumors plays a critical
role in tumor development and progression. Immune cells are important constituents of this …

Mechanistic insights and the clinical prospects of targeted therapies for glioblastoma: a comprehensive review

Y Shen, DKH Thng, ALA Wong, TB Toh - Experimental Hematology & …, 2024 - Springer
Glioblastoma (GBM) is a fatal brain tumour that is traditionally diagnosed based on
histological features. Recent molecular profiling studies have reshaped the World Health …

Integrin receptor-targeted, doxorubicin-loaded cerium oxide nanoparticles delivery to combat glioblastoma

G Koula, V Yakati, HK Rachamalla, K Bhamidipati… - …, 2024 - Taylor & Francis
Aim: To assess the chemo-immunomodulatory effects of doxorubicin-loaded cerium oxide
nanoparticles coated with oleyl amine-linked cyclic RGDfK peptide (CeNP+ Dox+ RGD) to …

Glioblastoma microenvironment—from biology to therapy

ZM Tapp, P Rajappa… - Genes & …, 2024 - genesdev.cshlp.org
Glioblastoma (GBM) is the most aggressive primary brain cancer. These tumors exhibit high
intertumoral and intratumoral heterogeneity in neoplastic and nonneoplastic compartments …

Emerging Therapies for Glioblastoma

SA Rios, S Oyervides, D Uribe, AM Reyes, V Fanniel… - Cancers, 2024 - mdpi.com
Simple Summary Glioblastoma is the most common malignant brain cancer and is
associated with poor prognosis, with an average survival after diagnosis of less than 18 …

合成生物学在基于微生物载体肿瘤疫苗设计中的应用

谭子斌, 梁康, 陈有海 - 合成生物学, 2024 - synbioj.cip.com.cn
合成生物学有望创造具备独特优势的抗肿瘤微生物疫苗, 合成生物学改造的微生物更能适应肿瘤
微环境并在其中富集与增殖, 削弱或者逆转免疫抑制细胞的功能, 并增强肿瘤抗原的呈递 …

The long-term effectiveness and mechanism of oncolytic virotherapy combined with anti-PD-L1 antibody in colorectal cancer patient

H Zhang, Y Ren, F Wang, X Tu, Z Tong, L Liu… - Cancer Gene …, 2024 - nature.com
Colorectal cancer (CRC) is known to be resistant to immunotherapy. In our phase-I clinical
trial, one patient achieved a 313-day prolonged response during the combined treatment of …

Efficient Delivery of Lomitapide using Hybrid Membrane‐Coated Tetrahedral DNA Nanostructures for Glioblastoma Therapy

M Song, J Tian, L Wang, S Dong, K Fu… - Advanced …, 2024 - Wiley Online Library
Glioblastoma (GBM) is the most aggressive and prevalent primary malignant tumor of the
central nervous system. Traditional chemotherapy has poor therapeutic effects and …