[HTML][HTML] Changes in malaria epidemiology in Africa and new challenges for elimination

IN Nkumama, WP O'meara, FHA Osier - Trends in parasitology, 2017 - cell.com
Although the burden of Plasmodium falciparum malaria is gradually declining in many parts
of Africa, it is characterized by spatial and temporal variability that presents new and …

[HTML][HTML] Examining the human infectious reservoir for Plasmodium falciparum malaria in areas of differing transmission intensity

BP Gonçalves, MC Kapulu, P Sawa… - Nature …, 2017 - nature.com
A detailed understanding of the human infectious reservoir is essential for improving malaria
transmission-reducing interventions. Here we report a multi-regional assessment of …

Within‐host modeling of blood‐stage malaria

DS Khoury, R Aogo… - Immunological …, 2018 - Wiley Online Library
Malaria infection continues to be a major health problem worldwide and drug resistance in
the major human parasite species, Plasmodium falciparum, is increasing in South East Asia …

[HTML][HTML] Health disparities across the counties of Kenya and implications for policy makers, 1990–2016: a systematic analysis for the Global Burden of Disease Study …

T Achoki, MK Miller-Petrie, SD Glenn, N Kalra… - The Lancet Global …, 2019 - thelancet.com
Summary Background The Global Burden of Diseases, Injuries, and Risk Factors Study
(GBD) 2016 provided comprehensive estimates of health loss globally. Decision makers in …

[HTML][HTML] Malaria infection, disease and mortality among children and adults on the coast of Kenya

A Kamau, G Mtanje, C Mataza, G Mwambingu, N Mturi… - Malaria journal, 2020 - Springer
Background Malaria transmission has recently fallen in many parts of Africa, but systematic
descriptions of infection and disease across all age groups are rare. Here, an …

Plasmodium falciparum adapts its investment into replication versus transmission according to the host environment

AI Abdi, F Achcar, L Sollelis, JL Silva-Filho, K Mwikali… - Elife, 2023 - elifesciences.org
The malaria parasite life cycle includes asexual replication in human blood, with a
proportion of parasites differentiating to gametocytes required for transmission to …

[HTML][HTML] The current malaria morbidity and mortality in different transmission settings in Western Kenya

A Kapesa, EJ Kweka, H Atieli, YA Afrane… - PloS one, 2018 - journals.plos.org
Background Passive surveillance of malaria in health facilities remains vital for
implementation of control and elimination programs. It is therefore essential understanding …

[HTML][HTML] The epidemiology of severe malaria at Manhiça District Hospital, Mozambique: a retrospective analysis of 20 years of malaria admissions surveillance data

C Guinovart, B Sigaúque, Q Bassat… - The Lancet Global …, 2022 - thelancet.com
Background Most malaria burden estimates rely on modelling infection prevalence to case
incidence data, with insufficient attention having been paid to the changing clinical …

Malaria infection and severe disease risks in Africa

RS Paton, A Kamau, S Akech, A Agweyu, M Ogero… - Science, 2021 - science.org
The relationship between community prevalence of Plasmodium falciparum and the burden
of severe, life-threatening disease remains poorly defined. To examine the three most …

[HTML][HTML] Observational study: 27 years of severe malaria surveillance in Kilifi, Kenya

P Njuguna, K Maitland, A Nyaguara, D Mwanga… - BMC medicine, 2019 - Springer
Abstract Background Many parts of Africa have witnessed reductions in Plasmodium
falciparum transmission over the last 15 years. Since immunity to malaria is acquired more …