Extra-and intra-ovarian factors in polycystic ovary syndrome: impact on oocyte maturation and embryo developmental competence

J Qiao, HL Feng - Human reproduction update, 2011 - academic.oup.com
BACKGROUND Polycystic ovary syndrome (PCOS) is a common metabolic dysfunction and
heterogeneous endocrine disorder in women of reproductive age. Although patients with …

[HTML][HTML] The role of macrophages in polycystic ovarian syndrome and its typical pathological features: A narrative review

Y Feng, Z Tang, W Zhang - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Polycystic ovarian syndrome (PCOS) is the most common endocrine and metabolic disorder
in women of childbearing age, with ovulatory dysfunction, hyperandrogenism, and polycystic …

Characterization of microRNA profile in human cumulus granulosa cells: Identification of microRNAs that regulate Notch signaling and are associated with PCOS

B Xu, YW Zhang, XH Tong, YS Liu - Molecular and cellular endocrinology, 2015 - Elsevier
Context Polycystic ovary syndrome (PCOS), a complex and heterogeneous endocrine
condition, is characterized by polycystic ovaries, hyperandrogenism, insulin resistance and …

Endoplasmic reticulum stress activated by androgen enhances apoptosis of granulosa cells via induction of death receptor 5 in PCOS

JMK Azhary, M Harada, N Takahashi, E Nose… - …, 2019 - academic.oup.com
Polycystic ovary syndrome (PCOS) is associated with hyperandrogenism and growth arrest
of antral follicles. Previously, we found that endoplasmic reticulum (ER) stress is activated in …

Oxidative status in granulosa cells of infertile women undergoing IVF

NB Karuputhula, R Chattopadhyay… - Systems biology in …, 2013 - Taylor & Francis
Studies on elevated reactive oxygen species (ROS) levels in granulosa cells (GC) and its
subsequent effect on fertilization are limited. Oxidative stress (OS) mediated alterations in …

IL-15 participates in the pathogenesis of polycystic ovary syndrome by affecting the activity of granulosa cells

Y Liu, Z Li, Y Wang, Q Cai, H Liu, C Xu… - Frontiers in …, 2022 - frontiersin.org
Background Low-grade chronic inflammation may contribute to the pathogenesis of
polycystic ovary syndrome (PCOS). Interleukin-15 (IL-15) is a proinflammatory cytokine …

Prolactin secretion patterns: basic mechanisms and clinical implications for reproduction

M Egli, B Leeners, THC Kruger - Reproduction, 2010 - rep.bioscientifica.com
Low progesterone concentrations during the bovine oestrous cycle induce enhanced
responsiveness to oxytocin challenge late in the luteal phase of the same cycle. The …

Functional characterization of microRNA-27a-3p expression in human polycystic ovary syndrome

M Wang, J Sun, B Xu, M Chrusciel, J Gao… - …, 2018 - academic.oup.com
The goal of this study was to characterize the function of microRNA-27a-3p (miR-27a-3p) in
polycystic ovary syndrome (PCOS). miR-27a-3p expression was analyzed in excised …

The blood-follicle barrier (BFB) in disease and in ovarian function

MKY Siu, CY Cheng - Biology and regulation of blood-tissue barriers, 2013 - Springer
The blood-follicle barrier (BFB) is one of the blood-tissue barriers in mammalian body found
in developing follicles in the ovary. The BFB, besides the tight junction^(TJ)-permeability …

Aberrant expression of long noncoding RNAs in cumulus cells isolated from PCOS patients

X Huang, C Hao, H Bao, M Wang, H Dai - Journal of assisted reproduction …, 2016 - Springer
Purpose To describe the long noncoding RNA (lncRNA) profiles in cumulus cells isolated
from polycystic ovary syndrome (PCOS) patients by employing a microarray and in-depth …