A Rigorous Framework for Calculating Protein–Protein Binding Affinities in Membranes
Calculating the binding free energy of integral transmembrane (TM) proteins is crucial for
understanding the mechanisms by which they recognize one another and reversibly …
understanding the mechanisms by which they recognize one another and reversibly …
Self‐Assembly of Photosynthetic Membranes
Bacterial photosynthetic membranes, also known as chromatophores, are tightly packed
with integral membrane proteins that work together to carry out photosynthesis …
with integral membrane proteins that work together to carry out photosynthesis …
Multidimensional umbrella sampling and replica‐exchange molecular dynamics simulations for structure prediction of transmembrane helix dimers
PC Li, N Miyashita, W Im, S Ishido… - Journal of …, 2014 - Wiley Online Library
Structural information of a transmembrane (TM) helix dimer is useful in understanding
molecular mechanisms of important biological phenomena such as signal transduction …
molecular mechanisms of important biological phenomena such as signal transduction …
Applications of the molecular dynamics flexible fitting method
In recent years, cryo-electron microscopy (cryo-EM) has established itself as a key method in
structural biology, permitting the structural characterization of large biomolecular complexes …
structural biology, permitting the structural characterization of large biomolecular complexes …
[HTML][HTML] Experimental evidence that the membrane-spanning helix of PufX adopts a bent conformation that facilitates dimerisation of the Rhodobacter sphaeroides RC …
EC Ratcliffe, RB Tunnicliffe, IW Ng, PG Adams… - … et Biophysica Acta (BBA …, 2011 - Elsevier
The PufX polypeptide is an integral component of some photosynthetic bacterial reaction
center-light harvesting 1 (RC–LH1) core complexes. Many aspects of the structure of PufX …
center-light harvesting 1 (RC–LH1) core complexes. Many aspects of the structure of PufX …
Molecular dynamics simulations of the interactions of kinin peptides with an anionic POPG bilayer
M Manna, C Mukhopadhyay - Langmuir, 2011 - ACS Publications
We have performed molecular dynamics simulations of peptide hormone bradykinin (BK)
and its fragment des-Arg9-BK in the presence of an anionic lipid bilayer, with an aim toward …
and its fragment des-Arg9-BK in the presence of an anionic lipid bilayer, with an aim toward …
Energy transfer dynamics in an RC–LH1–PufX tubular photosynthetic membrane
Light absorption and the subsequent transfer of excitation energy are the first two steps in
the photosynthetic process, carried out by protein-bound pigments, mainly …
the photosynthetic process, carried out by protein-bound pigments, mainly …
Native architecture of the photosynthetic membrane from Rhodobacter veldkampii
The photosynthetic membrane in purple bacteria contains several pigment–protein
complexes that assure light capture and establishment of the chemiosmotic gradient. The …
complexes that assure light capture and establishment of the chemiosmotic gradient. The …
[HTML][HTML] Cross-species investigation of the functions of the Rhodobacter PufX polypeptide and the composition of the RC–LH1 core complex
LI Crouch, MR Jones - Biochimica et Biophysica Acta (BBA)-Bioenergetics, 2012 - Elsevier
In well-characterised species of the Rhodobacter (Rba.) genus of purple photosynthetic
bacteria it is known that the photochemical reaction centre (RC) is intimately-associated with …
bacteria it is known that the photochemical reaction centre (RC) is intimately-associated with …
Formation of salt bridges mediates internal dimerization of myosin VI medial tail domain
The unconventional motor protein, myosin VI, is known to dimerize upon cargo binding to its
C-terminal end. It has been shown that one of its tail domains, called the medial tail domain …
C-terminal end. It has been shown that one of its tail domains, called the medial tail domain …