Linking prenatal environmental exposures to lifetime health with epigenome-wide association studies: state-of-the-science review and future recommendations
Background: The prenatal environment influences lifetime health; epigenetic mechanisms
likely predominate. In 2016, the first international consortium paper on cigarette smoking …
likely predominate. In 2016, the first international consortium paper on cigarette smoking …
Metabolic derangement by Arsenic: a review of the mechanisms
K Bibha, TM Akhigbe, MA Hamed… - Biological Trace Element …, 2024 - Springer
Studies have implicated arsenic exposure in various pathological conditions, including
metabolic disorders, which have become a global phenomenon, affecting developed …
metabolic disorders, which have become a global phenomenon, affecting developed …
Arsenic exposure, blood DNA methylation, and cardiovascular disease
A Domingo-Relloso, K Makhani… - Circulation …, 2022 - Am Heart Assoc
Background: Epigenetic dysregulation has been proposed as a key mechanism for arsenic-
related cardiovascular disease (CVD). We evaluated differentially methylated positions …
related cardiovascular disease (CVD). We evaluated differentially methylated positions …
Update of the risk assessment of inorganic arsenic in food
EFSA Panel on Contaminants in the Food Chain … - EFSA …, 2024 - Wiley Online Library
Abstract The European Commission asked EFSA to update its 2009 risk assessment on
arsenic in food carrying out a hazard assessment of inorganic arsenic (iAs) and using the …
arsenic in food carrying out a hazard assessment of inorganic arsenic (iAs) and using the …
Prenatal metal exposure, cord blood DNA methylation and persistence in childhood: an epigenome-wide association study of 12 metals
Background Prenatal exposure to essential and non-essential metals impacts birth and child
health, including fetal growth and neurodevelopment. DNA methylation (DNAm) may be …
health, including fetal growth and neurodevelopment. DNA methylation (DNAm) may be …
Epigenetics as a biomarker for early-life environmental exposure
R Schrott, A Song, C Ladd-Acosta - Current environmental health reports, 2022 - Springer
Abstract Purpose of Review There is interest in evaluating the developmental origins of
health and disease (DOHaD) which emphasizes the role of prenatal and early-life …
health and disease (DOHaD) which emphasizes the role of prenatal and early-life …
Exposure to arsenite in CD-1 mice during juvenile and adult stages: Effects on intestinal microbiota and gut-associated immune status
K Gokulan, MG Arnold, J Jensen, M Vanlandingham… - MBio, 2018 - Am Soc Microbiol
Intestinal microbiota composition and gut-associated immune response can contribute to the
toxicity of arsenic. We investigated the potential toxicity of short-term arsenic exposure on …
toxicity of arsenic. We investigated the potential toxicity of short-term arsenic exposure on …
Developmental exposure to endocrine disrupting chemicals and type 1 diabetes mellitus
SG Howard - Frontiers in endocrinology, 2018 - frontiersin.org
Exposure to endocrine disrupting chemicals (EDCs) may have implications for the
development of type 1 diabetes mellitus (T1DM), especially if exposure occurs during …
development of type 1 diabetes mellitus (T1DM), especially if exposure occurs during …
Inter‐and Transgenerational Effects of Paternal Exposure to Inorganic Arsenic
The rise of metabolic disorders in modern times is mainly attributed to the environment.
However, heritable effects of environmental chemicals on mammalian offsprings' metabolic …
However, heritable effects of environmental chemicals on mammalian offsprings' metabolic …
[HTML][HTML] DNA methylation 101: what is important to know about DNA methylation and its role in SLE risk and disease heterogeneity
CM Lanata, SA Chung, LA Criswell - Lupus science & medicine, 2018 - lupus.bmj.com
SLE is a complex autoimmune disease that results from the interplay of genetics,
epigenetics and environmental exposures. DNA methylation is an epigenetic mechanism …
epigenetics and environmental exposures. DNA methylation is an epigenetic mechanism …