Linking prenatal environmental exposures to lifetime health with epigenome-wide association studies: state-of-the-science review and future recommendations

KM Bakulski, F Blostein, SJ London - Environmental health …, 2023 - ehp.niehs.nih.gov
Background: The prenatal environment influences lifetime health; epigenetic mechanisms
likely predominate. In 2016, the first international consortium paper on cigarette smoking …

Metabolic derangement by Arsenic: a review of the mechanisms

K Bibha, TM Akhigbe, MA Hamed… - Biological Trace Element …, 2024 - Springer
Studies have implicated arsenic exposure in various pathological conditions, including
metabolic disorders, which have become a global phenomenon, affecting developed …

Arsenic exposure, blood DNA methylation, and cardiovascular disease

A Domingo-Relloso, K Makhani… - Circulation …, 2022 - Am Heart Assoc
Background: Epigenetic dysregulation has been proposed as a key mechanism for arsenic-
related cardiovascular disease (CVD). We evaluated differentially methylated positions …

Update of the risk assessment of inorganic arsenic in food

EFSA Panel on Contaminants in the Food Chain … - EFSA …, 2024 - Wiley Online Library
Abstract The European Commission asked EFSA to update its 2009 risk assessment on
arsenic in food carrying out a hazard assessment of inorganic arsenic (iAs) and using the …

Prenatal metal exposure, cord blood DNA methylation and persistence in childhood: an epigenome-wide association study of 12 metals

AK Bozack, SL Rifas-Shiman, BA Coull… - Clinical …, 2021 - Springer
Background Prenatal exposure to essential and non-essential metals impacts birth and child
health, including fetal growth and neurodevelopment. DNA methylation (DNAm) may be …

Epigenetics as a biomarker for early-life environmental exposure

R Schrott, A Song, C Ladd-Acosta - Current environmental health reports, 2022 - Springer
Abstract Purpose of Review There is interest in evaluating the developmental origins of
health and disease (DOHaD) which emphasizes the role of prenatal and early-life …

Exposure to arsenite in CD-1 mice during juvenile and adult stages: Effects on intestinal microbiota and gut-associated immune status

K Gokulan, MG Arnold, J Jensen, M Vanlandingham… - MBio, 2018 - Am Soc Microbiol
Intestinal microbiota composition and gut-associated immune response can contribute to the
toxicity of arsenic. We investigated the potential toxicity of short-term arsenic exposure on …

Developmental exposure to endocrine disrupting chemicals and type 1 diabetes mellitus

SG Howard - Frontiers in endocrinology, 2018 - frontiersin.org
Exposure to endocrine disrupting chemicals (EDCs) may have implications for the
development of type 1 diabetes mellitus (T1DM), especially if exposure occurs during …

Inter‐and Transgenerational Effects of Paternal Exposure to Inorganic Arsenic

Y Gong, Y Xue, X Li, Z Zhang, W Zhou… - Advanced …, 2021 - Wiley Online Library
The rise of metabolic disorders in modern times is mainly attributed to the environment.
However, heritable effects of environmental chemicals on mammalian offsprings' metabolic …

[HTML][HTML] DNA methylation 101: what is important to know about DNA methylation and its role in SLE risk and disease heterogeneity

CM Lanata, SA Chung, LA Criswell - Lupus science & medicine, 2018 - lupus.bmj.com
SLE is a complex autoimmune disease that results from the interplay of genetics,
epigenetics and environmental exposures. DNA methylation is an epigenetic mechanism …