With the development of artificial intelligence (AI), tailoring methods for enzyme engineering
have been widely expanded. Additional protocols based on optimized network models have …

Abstract Machine learning (ML) is becoming increasingly crucial in many fields of
engineering but has not yet played out its full potential in bioprocess engineering. While …

Diabetes is a global epidemic. Long-term exposure to hyperglycemia can cause chronic
damage to various tissues. Thus, early diagnosis of diabetes is crucial. In this study, we …

Background: Thermophilic proteins can maintain good activity under high temperature,
therefore, it is important to study thermophilic proteins for the thermal stability of proteins …

Recently, several machine-learning-based DNA N-4-methycytosine (4mC) predictors have
been developed to provide deeper insight into the biological functions and mechanisms of …

The advent of high-throughput genomic technologies has resulted in the accumulation of
massive amounts of genomic information. However, biologists are challenged with how to …

The human body has a huge variety of enzymes, each of which contributes to the
acceleration of a certain kind of biochemical reaction. The majority of metabolic processes in …

Motivation The biological function of N 6-methyladenine DNA (6mA) in plants is largely
unknown. Rice is one of the most important crops worldwide and is a model species for …

N4-methylcytosine as one kind of modification of DNA has a critical role which alters genetic
performance such as protein interactions, conformation, stability in DNA as well as the …

Among DNA modifications, N4-methylcytosine (4mC) is one of the most significant ones, and
it is linked to the development of cell proliferation and gene expression. To know different its …