[HTML][HTML] Factors affecting the optimisation and scale-up of lipid accumulation in oleaginous yeasts for sustainable biofuels production

R Robles-Iglesias, C Naveira-Pazos… - … and Sustainable Energy …, 2023 - Elsevier
The recent unprecedented increase in energy demand has led to a growing interest in
emerging alternatives such as the production of microbial lipids with high energy density …

[HTML][HTML] Yarrowia lipolytica Strains and Their Biotechnological Applications: How Natural Biodiversity and Metabolic Engineering Could Contribute to Cell Factories …

C Madzak - Journal of Fungi, 2021 - mdpi.com
Among non-conventional yeasts of industrial interest, the dimorphic oleaginous yeast
Yarrowia lipolytica appears as one of the most attractive for a large range of white …

[HTML][HTML] Acyl-CoA: diacylglycerol acyltransferase: Properties, physiological roles, metabolic engineering and intentional control

G Chen, JL Harwood, MJ Lemieux, SJ Stone… - Progress in Lipid …, 2022 - Elsevier
Acyl-CoA: diacylglycerol acyltransferase (DGAT, EC 2.3. 1.20) catalyzes the last reaction in
the acyl-CoA-dependent biosynthesis of triacylglycerol (TAG). DGAT activity resides mainly …

Reprogramming the fatty acid metabolism of Yarrowia lipolytica to produce the customized omega-6 polyunsaturated fatty acids

J Wang, X Yu, K Wang, L Lin, HH Liu… - Bioresource …, 2023 - Elsevier
Omega-6 polyunsaturated fatty acids (ω6-PUFAs), such as γ-linolenic acid (GLA), dihomo-γ-
linolenic acid (DGLA) and arachidonic acid (ARA), are indispensable nutrients for human …

Approaches to improve the lipid synthesis of oleaginous yeast Yarrowia lipolytica: A review

W Bao, Z Li, X Wang, R Gao, X Zhou, S Cheng… - … and Sustainable Energy …, 2021 - Elsevier
Microbial oils have become a research hotspot in alleviating energy challenges and
environmental problems because of their potential to be green alternatives of traditional …

Combining orthogonal plant and non-plant fatty acid biosynthesis pathways for efficient production of microbial oil enriched in nervonic acid in Yarrowia lipolytica

K Wang, L Lin, P Wei, R Ledesma-Amaro, XJ Ji - Bioresource Technology, 2023 - Elsevier
Nervonic acid has proven efficacy in brain development and the prevention of
neurodegenerative diseases. Here, an alternative and sustainable strategy for nervonic acid …

Advances in synthetic biology tools paving the way for the biomanufacturing of unusual fatty acids using the Yarrowia lipolytica chassis

K Wang, TQ Shi, L Lin, P Wei, R Ledesma-Amaro… - Biotechnology …, 2022 - Elsevier
Unusual fatty acids with special carbon chain length or functional groups have been
extensively used in the chemical, material, nutraceutical, and pharmaceutical industries. The …

Remodelling metabolism for high-level resveratrol production in Yarrowia lipolytica

M Liu, C Wang, X Ren, S Gao, S Yu, J Zhou - Bioresource Technology, 2022 - Elsevier
Resveratrol is a polyphenol with numerous applications in food, pharma, and cosmetics.
Lack of precursors and low titer are the main problems hindering industrial scale resveratrol …

Engineering the Lipid and Fatty Acid Metabolism in Yarrowia lipolytica for Sustainable Production of High Oleic Oils

K Wang, TQ Shi, J Wang, P Wei… - ACS Synthetic …, 2022 - ACS Publications
Oleic acid is widely applied in the chemical, material, nutritional, and pharmaceutical
industries. However, the current production of oleic acid via high oleic plant oils is limited by …

Synthetic fuels: what are they and where do they come from?

JC Ruth, G Stephanopoulos - Current Opinion in Biotechnology, 2023 - Elsevier
Highlights•Synthetic fuels offer novel solutions to energy and environmental
challenges.•Synthetic fuels can be grouped based on their synthesis strategies.• …