Nutrimetabolomics: an integrative action for metabolomic analyses in human nutritional studies
MM Ulaszewska, CH Weinert… - Molecular nutrition & …, 2019 - Wiley Online Library
The life sciences are currently being transformed by an unprecedented wave of
developments in molecular analysis, which include important advances in instrumental …
developments in molecular analysis, which include important advances in instrumental …
Metabolomics-based methods for early disease diagnostics
The emerging field of metabolomics, in which a large number of small-molecule metabolites
from body fluids or tissues are detected quantitatively in a single step, promises immense …
from body fluids or tissues are detected quantitatively in a single step, promises immense …
Analytical strategies in metabonomics
EM Lenz, ID Wilson - Journal of proteome research, 2007 - ACS Publications
To perform metabonomics investigations, it is necessary to generate comprehensive
metabolite profiles for complex samples such as biofluids and tissue/tissue extracts …
metabolite profiles for complex samples such as biofluids and tissue/tissue extracts …
LC-MS-based methodology for global metabolite profiling in metabonomics/metabolomics
In order to perform metabonomic investigations, it is necessary to generate comprehensive
“global” metabolite profiles from complex samples, such as biofluids and tissues/tissue …
“global” metabolite profiles from complex samples, such as biofluids and tissues/tissue …
Gas chromatography/mass spectrometry in metabolic profiling of biological fluids
One of the objectives of metabonomics is to identify subtle changes in metabolite profiles
between biological systems of different physiological or pathological states. Gas …
between biological systems of different physiological or pathological states. Gas …
Current trends and future requirements for the mass spectrometric investigation of microbial, mammalian and plant metabolomes
WB Dunn - Physical biology, 2008 - iopscience.iop.org
The functional levels of biological cells or organisms can be separated into the genome,
transcriptome, proteome and metabolome. Of these the metabolome offers specific …
transcriptome, proteome and metabolome. Of these the metabolome offers specific …
Knowledge discovery in metabolomics: an overview of MS data handling
While metabolomics attempts to comprehensively analyse the small molecules
characterising a biological system, MS has been promoted as the gold standard to study the …
characterising a biological system, MS has been promoted as the gold standard to study the …
Development and performance of a gas chromatography− time-of-flight mass spectrometry analysis for large-scale nontargeted metabolomic studies of human serum
P Begley, S Francis-McIntyre, WB Dunn… - Analytical …, 2009 - ACS Publications
A method for the preparation and GC− TOF-MS analysis of human serum samples has been
developed and evaluated for application in long-term metabolomic studies. Serum samples …
developed and evaluated for application in long-term metabolomic studies. Serum samples …
[PDF][PDF] Metabolomics in diabetes research
N Friedrich - Journal of Endocrinology, 2012 - Citeseer
Diabetes represents one of the most important global health problems because it is
associated with a large economic burden for the health systems of many countries. Whereas …
associated with a large economic burden for the health systems of many countries. Whereas …
Proline betaine and its biotransformation products in fasting urine samples are potential biomarkers of habitual citrus fruit consumption
AJ Lloyd, M Beckmann, G Favé, JC Mathers… - British Journal of …, 2011 - cambridge.org
The lack of robust measures of dietary exposure hinders a quantitative understanding of
causal relationships between diet and health. Non-targeted metabolite fingerprinting was …
causal relationships between diet and health. Non-targeted metabolite fingerprinting was …