[HTML][HTML] Obesity‑a risk factor for increased COVID‑19 prevalence, severity and lethality

D Petrakis, D Margină… - Molecular …, 2020 - build.spandidos-publications.com
Abstract Coronaviruses (CoVs), enveloped positive-sense RNA viruses, are a group of
viruses that cause infections in the human respiratory tract, which can be characterized …

[HTML][HTML] Characterization of the internal working-life exposome using minimally and non-invasive sampling methods-a narrative review

E Verscheure, R Stierum, V Schlünssen… - Environmental …, 2023 - Elsevier
During recent years, we are moving away from the 'one exposure, one disease'-approach in
occupational settings and towards a more comprehensive approach, taking into account the …

Role of β2-adrenergic receptors in chronic obstructive pulmonary disease

A Yang, G Yu, Y Wu, H Wang - Life Sciences, 2021 - Elsevier
Abstract Beta-2 adrenergic receptors (β2-ARs) have important roles in the pathogenesis and
treatment of chronic obstructive pulmonary disease (COPD). In recent years, progress has …

Associations between Selected ADRB1 and CYP2D6 Gene Polymorphisms in Children with Ventricular and Supraventricular Arrhythmias

E Moric-Janiszewska, S Smolik, L Szydłowski… - Medicina, 2023 - mdpi.com
Background and Objectives: Tachycardia is a common cardiovascular disease. Drugs
blocking β1-adrenergic receptors (ADRB1) are used in the therapy of arrhythmogenic heart …

G protein-coupled receptor (GPCR) pharmacogenomics

MD Thompson, D Reiner-Link, A Berghella… - Critical Reviews in …, 2024 - Taylor & Francis
The field of pharmacogenetics, the investigation of the influence of one or more sequence
variants on drug response phenotypes, is a special case of pharmacogenomics, a discipline …

Identification and characterization of adipose surface epitopes

Y Onogi, AEMM Khalil, S Ussar - Biochemical Journal, 2020 - portlandpress.com
Adipose tissue is a central regulator of metabolism and an important pharmacological target
to treat the metabolic consequences of obesity, such as insulin resistance and dyslipidemia …

Medium‐Dose Formoterol Attenuated Abdominal Aortic Aneurysm Induced by EPO via β2AR/cAMP/SIRT1 Pathway

J Zhang, Y Cao, R Ren, W Sui, Y Zhang… - Advanced …, 2024 - Wiley Online Library
Abdominal aortic aneurysm (AAA) is a life‐threatening vascular disease but effective drugs
for treatment of AAA are still lacking. Recently, erythropoietin (EPO) is reported to induce …

Heart failure with reduced ejection fraction and atrial fibrillation: A sub‐Saharan African perspective

N Mboweni, M Maseko, N Tsabedze - ESC Heart Failure, 2023 - Wiley Online Library
Cardiovascular diseases are a well‐established cause of death in high‐income countries. In
the last 20 years, Sub‐Saharan Africa (SSA) has seen one of the sharpest increases in …

Role of β-blockers in preventing heart failure and major adverse cardiac events post myocardial infarction

N Johri, PS Matreja, A Maurya… - Current Cardiology …, 2023 - ingentaconnect.com
β-blockers have been widely utilized as a part of acute myocardial infarction (AMI) treatment
for the past 40 years. Patients receiving β-adrenergic blockers for an extended period …

Beta-adrenergic receptor polymorphism and patho-genetics of trauma: a transformational frontier of personalized medicine in neurotrauma

A El-Menyar, NA Khan, M Asim, S Rizoli… - Journal of …, 2024 - liebertpub.com
Trauma is a serious public health issue, and remains a major cause of mortality and
disability worldwide. The notion that genetic factors contribute to an individual's response to …