Alzheimer's disease is a severe irreversible syndrome, characterized by a slow and
progressive cognitive decline that interferes with the standard instrumental and essential …

The Precision Neurology development process implements systems theory with system
biology and neurophysiology in a parallel, bidirectional research path: a combined …

Background Local network connectivity disruptions in Alzheimer's disease patients have
been found using graph analysis in BOLD fMRI. Other studies using MEG and cortical …

Normal aging is associated with cognitive decline. Functions such as attention, information
processing, and working memory are compromised. It has been hypothesized that not only …

Recent research on Alzheimer's disease (AD) has shown that cognitive and memory decline
in this disease is accompanied by disrupted changes in the coordination of large-scale brain …

Here we utilized resting-state functional magnetic resonance imaging (R-fMRI) to measure
the amplitude of low-frequency fluctuations (ALFF) and fractional ALFF (fALFF) in 24 patients …

Recent functional imaging studies have indicated that the pathophysiology of Alzheimer's
disease (AD) can be associated with the changes in spontaneous low-frequency (< 0.08 Hz) …

Alzheimer's disease (AD) is characterized by a heterogeneous distribution of pathological
changes throughout the brain. Magnetic resonance imaging can be used to investigate the …

We used resting‐state functional MRI to investigate spatial patterns of spontaneous brain
activity in 22 healthy elderly subjects, as well as 16 mild cognitive impairment (MCI) and 16 …

Introduction Alzheimer's disease (AD) usually first presents in elderly patients, but may also
develop at an earlier age. Patients with an early age at onset tend to present with complaints …