[HTML][HTML] Neonatal hypoxia ischaemia: mechanisms, models, and therapeutic challenges

LJ Millar, L Shi, A Hoerder-Suabedissen… - Frontiers in cellular …, 2017 - frontiersin.org
Neonatal hypoxia-ischaemia (HI) is the most common cause of death and disability in
human neonates, and is often associated with persistent motor, sensory, and cognitive …

Animal models for neonatal brain injury induced by hypoxic ischemic conditions in rodents

N Hamdy, S Eide, HS Sun, ZP Feng - Experimental Neurology, 2020 - Elsevier
Neonatal hypoxia-ischemia and resulting encephalopathies are of significant concern.
Intrapartum asphyxia is a leading cause of neonatal death globally. Among surviving infants …

Prenatal opioid exposure: the next neonatal neuroinflammatory disease

LL Jantzie, JR Maxwell, JC Newville… - Brain, behavior, and …, 2020 - Elsevier
The rates of opioid use disorder during pregnancy have more than quadrupled in the last
decade, resulting in numerous infants suffering exposure to opioids during the perinatal …

Interface‐Stabilized Fiber Sensor for Real‐Time Monitoring of Amniotic Fluid During Pregnancy

Q Li, D Li, J Lu, K Zou, L Wang, Y Jiao… - Advanced …, 2024 - Wiley Online Library
Diseases in pregnancy endanger millions of fetuses worldwide every year. The onset of
these diseases can be early warned by the dynamic abnormalities of biochemicals in …

Placental mediated mechanisms of perinatal brain injury: evolving inflammation and exosomes

AR Gall, S Amoah, Y Kitase, LL Jantzie - Experimental neurology, 2022 - Elsevier
Pregnancy is an inflammatory process that is carefully regulated by the placenta via
immunomodulation and cell-to-cell communication of maternal and fetal tissues. Exosomes …

[HTML][HTML] Soluble PD-L1 reprograms blood monocytes to prevent cerebral edema and facilitate recovery after ischemic stroke

JE Kim, RP Lee, E Yazigi, L Atta, J Feghali… - Brain, Behavior, and …, 2024 - Elsevier
Acute cerebral ischemia triggers a profound inflammatory response. While macrophages
polarized to an M2-like phenotype clear debris and facilitate tissue repair, aberrant or …

The fetus at the tipping point: modifying the outcome of fetal asphyxia

SK Dhillon, CA Lear, R Galinsky… - The Journal of …, 2018 - Wiley Online Library
Brain injury around birth is associated with nearly half of all cases of cerebral palsy.
Although brain injury is multifactorial, particularly after preterm birth, acute hypoxia …

Microstructural and microglial changes after repetitive mild traumatic brain injury in mice

S Robinson, JB Berglass, JL Denson… - Journal of …, 2017 - Wiley Online Library
Traumatic brain injury (TBI) is a major public health issue, with recently increased
awareness of the potential long‐term sequelae of repetitive injury. Although TBI is common …

Acute oligodendrocyte loss with persistent white matter injury in a third trimester equivalent mouse model of fetal alcohol spectrum disorder

J Newville, CF Valenzuela, L Li, LL Jantzie… - Glia, 2017 - Wiley Online Library
Alcohol exposure during central nervous system (CNS) development can lead to fetal
alcohol spectrum disorder (FASD). Human imaging studies have revealed significant white …

[HTML][HTML] Effects of pneumoperitoneum and steep Trendelenburg position on cerebral hemodynamics during robotic-assisted laparoscopic radical prostatectomy: A …

K Chen, L Wang, Q Wang, X Liu, Y Lu, Y Li, GTC Wong - Medicine, 2019 - journals.lww.com
Background: We evaluated the relationship between ultrasonographical acquired
parameters and short-term postoperative cognitive function in patients undergoing robotic …