The value of antimicrobial peptides in the age of resistance
M Magana, M Pushpanathan, AL Santos… - The lancet infectious …, 2020 - thelancet.com
Accelerating growth and global expansion of antimicrobial resistance has deepened the
need for discovery of novel antimicrobial agents. Antimicrobial peptides have clear …
need for discovery of novel antimicrobial agents. Antimicrobial peptides have clear …
[HTML][HTML] Membrane active antimicrobial peptides: translating mechanistic insights to design
J Li, JJ Koh, S Liu, R Lakshminarayanan… - Frontiers in …, 2017 - frontiersin.org
Antimicrobial peptides (AMPs) are promising next generation antibiotics that hold great
potential for combating bacterial resistance. AMPs can be both bacteriostatic and …
potential for combating bacterial resistance. AMPs can be both bacteriostatic and …
Paramagnetic chemical probes for studying biological macromolecules
Paramagnetic chemical probes have been used in electron paramagnetic resonance (EPR)
and nuclear magnetic resonance (NMR) spectroscopy for more than four decades. Recent …
and nuclear magnetic resonance (NMR) spectroscopy for more than four decades. Recent …
[HTML][HTML] Studies on anticancer activities of antimicrobial peptides
DW Hoskin, A Ramamoorthy - Biochimica et Biophysica Acta (BBA) …, 2008 - Elsevier
In spite of great advances in cancer therapy, there is considerable current interest in
developing anticancer agents with a new mode of action because of the development of …
developing anticancer agents with a new mode of action because of the development of …
[HTML][HTML] Antimicrobial peptides: an overview of a promising class of therapeutics
A Giuliani, G Pirri, S Nicoletto - Open Life Sciences, 2007 - degruyter.com
Antibiotic resistance is increasing at a rate that far exceeds the pace of new development of
drugs. Antimicrobial peptides, both synthetic and from natural sources, have raised interest …
drugs. Antimicrobial peptides, both synthetic and from natural sources, have raised interest …
[HTML][HTML] The magic of bicelles lights up membrane protein structure
UHN Dürr, M Gildenberg, A Ramamoorthy - Chemical reviews, 2012 - ACS Publications
Biological membranes and membrane proteins, responsible for numerous exciting
biological processes, present one of the paramount challenges in biophysics today …
biological processes, present one of the paramount challenges in biophysics today …
[HTML][HTML] Peptide–membrane interactions and mechanisms of membrane destruction by amphipathic α-helical antimicrobial peptides
H Sato, JB Feix - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2006 - Elsevier
Antimicrobial peptides (AMPs) have received considerable interest as a source of new
antibiotics with the potential for treatment of multiple-drug resistant infections. An important …
antibiotics with the potential for treatment of multiple-drug resistant infections. An important …
[HTML][HTML] Detergent-like actions of linear amphipathic cationic antimicrobial peptides
B Bechinger, K Lohner - Biochimica et Biophysica Acta (BBA) …, 2006 - Elsevier
Antimicrobial peptides have raised much interest as pathogens become resistant against
conventional antibiotics. We review biophysical studies that have been performed to better …
conventional antibiotics. We review biophysical studies that have been performed to better …
[HTML][HTML] Mode of action of the new antibiotic for Gram-positive pathogens daptomycin: comparison with cationic antimicrobial peptides and lipopeptides
SK Straus, REW Hancock - Biochimica et Biophysica Acta (BBA) …, 2006 - Elsevier
With the steady rise in the number of antibiotic-resistant Gram-positive pathogens, it has
become increasingly important to find new antibacterial agents which are highly active and …
become increasingly important to find new antibacterial agents which are highly active and …
[HTML][HTML] Alpha-helical antimicrobial peptides—Using a sequence template to guide structure–activity relationship studies
I Zelezetsky, A Tossi - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2006 - Elsevier
An important class of cytolytic antimicrobial peptides (AMPs) assumes an amphipathic, α-
helical conformation that permits efficient interaction with biological membranes. Host …
helical conformation that permits efficient interaction with biological membranes. Host …