A critical overview of current progress for COVID-19: development of vaccines, antiviral drugs, and therapeutic antibodies

M Kumari, RM Lu, MC Li, JL Huang, FF Hsu… - Journal of biomedical …, 2022 - Springer
The novel coronavirus disease (COVID-19) pandemic remains a global public health crisis,
presenting a broad range of challenges. To help address some of the main problems, the …

Effectiveness of heterologous and homologous covid-19 vaccine regimens: living systematic review with network meta-analysis

WY Au, PPH Cheung - Bmj, 2022 - bmj.com
Objective To evaluate the effectiveness of heterologous and homologous covid-19 vaccine
regimens with and without boosting in preventing covid-19 related infection, hospital …

Antiretroviral drugs for treatment and prevention of HIV infection in adults: 2022 recommendations of the International Antiviral Society–USA panel

RT Gandhi, R Bedimo, JF Hoy, RJ Landovitz, DM Smith… - Jama, 2023 - jamanetwork.com
Importance Recent advances in treatment and prevention of HIV warrant updated
recommendations to guide optimal practice. Objective Based on a critical evaluation of new …

Convalescent plasma or hyperimmune immunoglobulin for people with COVID‐19: a living systematic review

I Monsef, C Doree, EM Wood… - Cochrane Database …, 2020 - cochranelibrary.com
Background Convalescent plasma and hyperimmune immunoglobulin may reduce mortality
in patients with viral respiratory diseases, and are currently being investigated in trials as …

Impact of COVID-19 on immunocompromised populations during the Omicron era: insights from the observational population-based INFORM study

RA Evans, S Dube, Y Lu, M Yates… - The Lancet Regional …, 2023 - thelancet.com
Background Immunocompromised individuals are not optimally protected by COVID-19
vaccines and potentially require additional preventive interventions to mitigate the risk of …

Effect of a 2-week interruption in methotrexate treatment versus continued treatment on COVID-19 booster vaccine immunity in adults with inflammatory conditions …

A Abhishek, RJ Boyton, N Peckham… - The Lancet …, 2022 - thelancet.com
Background Immunosuppressive treatments inhibit vaccine-induced immunity against SARS-
CoV-2. We evaluated whether a 2-week interruption of methotrexate treatment immediately …

Response to additional COVID-19 vaccine doses in people who are immunocompromised: a rapid review

EPK Parker, S Desai, M Marti, H Nohynek… - The Lancet Global …, 2022 - thelancet.com
Individuals with compromised immune systems, whether because of immunodeficiency or
immuno suppressive therapy, are among those most susceptible to COVID19. In fact, people …

[HTML][HTML] Outcome of COVID-19 in hospitalised immunocompromised patients: An analysis of the WHO ISARIC CCP-UK prospective cohort study

L Turtle, M Thorpe, TM Drake, M Swets… - PLoS …, 2023 - journals.plos.org
Background Immunocompromised patients may be at higher risk of mortality if hospitalised
with Coronavirus Disease 2019 (COVID-19) compared with immunocompetent patients …

Changes in COVID-19-related mortality across key demographic and clinical subgroups in England from 2020 to 2022: a retrospective cohort study using the …

L Nab, EPK Parker, CD Andrews, WJ Hulme… - The Lancet public …, 2023 - thelancet.com
Background COVID-19 has been shown to differently affect various demographic and
clinical population subgroups. We aimed to describe trends in absolute and relative COVID …

Magnitude of venous or capillary blood-derived SARS-CoV-2-specific T cell response determines COVID-19 immunity

MJ Scurr, G Lippiatt, L Capitani, K Bentley… - Nature …, 2022 - nature.com
T cells specific for SARS-CoV-2 are thought to protect against infection and development of
COVID-19, but direct evidence for this is lacking. Here, we associated whole-blood-based …