Chronic obstructive pulmonary disease (COPD) was the fourth leading cause of death
worldwide in 2015. Current treatments for patients ease discomfort and help decrease …

Background: Chronic diseases arise as a consequence of an unhealthy lifestyle primarily
characterized by physical inactivity and unbalanced diets. Regular physical activity can …

Lifestyle interventions, including exercise and dietary supplementation, can modify DNA
methylation and exert health benefits; however, the underlying mechanisms are poorly …

Background and aims Lactylation, a recently identified post-translational modification (PTM),
plays a central role in the regulation of multiple physiological and pathological processes …

Epigenetic mechanisms have been suggested to play a role in the genetic regulation of
pathways related to inflammation. Therefore, we aimed to systematically review studies …

Physical inactivity and a poor diet increase systemic inflammation, while chronic
inflammation can be reduced through exercise and nutritional interventions. The …

Abstract The Veterans Health Administration (VHA) is the largest integrated healthcare
system in the United States (US) providing healthcare to an increasing number of middle …

Epigenetic changes have been shown to be associated with both aging process and aging-
related diseases. There is evidence regarding the benefits of physical activity on the …

Results All variables of the control-COPD group showed a non-significant improvement.
Except BMI and PFT, the pre-to-post comparison of the study group's parameters as cortisol …

Introduction: Although evidence suggests that physical exercise reduces systemic
inflammation, at the plasma level, there are still contradictions in chronic obstructive …