Cell-size space regulates the behavior of confined polymers: from nano-and micromaterials science to biology

M Yanagisawa, C Watanabe, N Yoshinaga… - Langmuir, 2022 - ACS Publications
Polymer micromaterials in a liquid or gel phase covered with a surfactant membrane are
widely used materials in pharmaceuticals, cosmetics, and foods. In particular, cell-sized …

Surfaces as frameworks for intracellular organization

G Rivas, AP Minton - Trends in Biochemical Sciences, 2024 - cell.com
A large fraction of soluble protein within the interior of living cells may reversibly associate
with structural elements, including proteinaceous fibers and phospholipid membranes. In …

Marangoni Droplets of Dextran in PEG Solution and Its Motile Change Due to Coil–Globule Transition of Coexisting DNA

T Furuki, H Sakuta, N Yanagisawa… - … Applied Materials & …, 2024 - ACS Publications
Motile droplets using Marangoni convection are attracting attention for their potential as cell-
mimicking small robots. However, the motion of droplets relative to the internal and external …

DNA compaction enhances the sensitivity of fluorescence-based nucleic acid assays: a game changer in point of care sensors?

S Sudarsan, A Prabhu, D Prasad, NK Mani - Analyst, 2023 - pubs.rsc.org
Fluorescence-based nucleic acid assays frequently exhibit a feeble signal at low analyte
concentrations, necessitating complex, expensive methods such as the development of …

Water‐in‐Water Droplets Selectively Uptake Self‐Assembled DNA Nano/Microstructures: a Versatile Method for Purification in DNA Nanotechnology

MK Masukawa, Y Sato, F Yu, K Tsumoto… - …, 2022 - Wiley Online Library
DNA is an excellent material for constructing self‐assembled nano/microstructures. Owing to
the widespread use of DNA as a building block in laboratories and industry, it is desirable to …

Stabilization of DNA-encapsulating droplets through negative charge at the droplet interface

M Shono, F Fujita, K Yoshikawa, A Shioi - Chemistry Letters, 2023 - academic.oup.com
It was found that stable cell-sized droplets entrapping DNA molecules are spontaneously
generated through micro segregation. To clarify the mechanism, we performed …

Self-emergent vortex flow of microtubule and kinesin in cell-sized droplets under water/water phase separation

H Sakuta, N Nakatani, T Torisawa, Y Sumino… - Communications …, 2023 - nature.com
By facilitating a water/water phase separation (w/wPS), crowded biopolymers in cells form
droplets that contribute to the spatial localization of biological components and their …

Coalescence of liquid or gel-like DNA-encapsulating microdroplets

T Nishio, H Schiessel - The Journal of Chemical Physics, 2024 - pubs.aip.org
Liquid–liquid phase separation plays a prominent role in the physics of life, providing the
cells with various membrane-less compartments. These structures exhibit a range of …

Crowding effect on the alignment of rod molecules confined in a spherical cavity

CY Shew, K Yoshikawa - Chemical Physics Letters, 2023 - Elsevier
Abstract We conduct Monte Carlo simulation for a simple model to elucidate alignments of
multiple rigid rods confined within a rigid spherical cavity under crowding. For rods shorter …

Predicting chromosomal compartments directly from the nucleotide sequence with DNA-DDA

X Lainscsek, L Taher - Briefings in Bioinformatics, 2023 - academic.oup.com
Abstract Three-dimensional (3D) genome architecture is characterized by multi-scale
patterns and plays an essential role in gene regulation. Chromatin conformation capturing …