The classical lytic infection theory along with large T antigen-mediated oncogenesis cannot
explain the BK polyomavirus (BKPyV)-associated tumor secondary to BKPyV-associated …

Background Following kidney transplantation, BK virus associated nephropathy (BKVN)
occurs in 1 to 10% of kidney transplant recipients (KTR) and represents a major cause of …

Renal transplantation is one of the primary approaches for curing end-stage kidney disease.
With advancements in immunosuppressive agents, the short-term and long-term survival …

Background: Kidney transplant recipients with BK virus infection are at risk of developing BK
virus-associated nephropathy, allograft rejection, and subsequent graft loss. There are no …

Background BK polyomavirus‐associated nephropathy (BKPyVAN) is an important cause of
allograft dysfunction and failure in kidney transplant recipients (KTRs) and there are no …

Introduction Immunosuppression after kidney transplantation (KTx) exposes recipients to
Human Polyomaviruses (HPyVs) infections, whose natural history is still misunderstood …

TO THE EDITOR—BK polyomavirus (BKPyV) continues to challenge kidney transplantation
(KT) outcomes with premature renal allograft failure, and evidence-based treatment …

Little is known about the urinary virome and how it interacts with the host, particularly in
renal transplant diseases. Using metagenomic sequencing, we characterized the urinary …

Developing safe and effective drugs and other medical products is a complex and costly
process. Drug development has been, historically, commonly competitive and …

Abstract Background Polyomavirus (PyV) nephropathy (PyVN) leads to kidney transplant
dysfunction and loss. Since a definitive diagnosis requires an invasive kidney biopsy, a …