Nanopore techniques offer a low-cost, label-free, and high-throughput platform that could be
used in single-molecule biosensing and in particular DNA sequencing. Since 2010 …

The cellular membrane constitutes one of the most fundamental compartments of a living
cell, where key processes such as selective transport of material and exchange of …

In this paper we review the current status of high-performance computing applications in the
general area of drug discovery. We provide an introduction to the methodologies applied at …

The scientific community has witnessed an exponential increase in the applications of
graphene and graphene-based materials in a wide range of fields, from engineering to …

A long-standing problem in the application of solid-state nanopores is the lack of the precise
control over the geometry of artificially formed pores compared to the well-defined geometry …

Pore-based structures occur widely in living organisms. Ion channels embedded in cell
membranes, for example, provide pathways, where electron and proton transfer are coupled …

Protein nanopores have been widely used as single-molecule sensors for the detection and
characterization of biological polymers such as DNA, RNA, and polypeptides. A variety of …

A detailed understanding of the interactions between biomolecules and nanomaterial
surfaces is critical for the development of biomedical applications of these nanomaterials …

DNA methylation is an epigenetic modification involving the addition of a methyl group to
DNA, which is heavily involved in gene expression and regulation, thereby critical to the …

Solid-state nanopore sequencing is now confronted with problems of stochastic pore
clogging and too fast speed during the DNA permeation through a nanopore, although this …