Contact guidance for cell outgrowth refers to the phenomenon of the topography of the
extracellular matrix regulating cell behaviors and functions. In tissue engineering, scaffolds …

The extracellular matrix (ECM) is a highly complex structure through which biochemical and
mechanical signals are transmitted. In processes of cell migration, the ECM also acts as a …

Environmental insults including respiratory infections, in combination with genetic
predisposition, may lead to lung diseases such as chronic obstructive pulmonary disease …

Biomechanics is a physical phenomenon which mainly related with deformation and
movement of life forms. As a mechanical signal, it participates in the growth and …

Cancer metastasis starts from early local invasion, during which tumor cells detach from the
primary tumor, penetrate the extracellular matrix (ECM), and then invade neighboring …

Bladder cancer (BC) is one of the most prevalent genitourinary cancers. Despite the growing
research interest in BC, the molecular mechanisms underlying its carcinogenesis remain …

Cancer as the leading cause of death worldwide has many issues that still need to be
addressed. Since the alterations on the glycan compositions or/and structures (ie …

SPARC/osteonectin, CWCV and Kazal-like domain proteoglycan (SPOCK) is a family of
highly conserved multidomain proteins. In total, three such family members, SPOCK1 …