Detection of alternative DNA structures and its implications for human disease
G Matos-Rodrigues, JA Hisey, A Nussenzweig… - Molecular Cell, 2023 - cell.com
Around 3% of the genome consists of simple DNA repeats that are prone to forming
alternative (non-B) DNA structures, such as hairpins, cruciforms, triplexes (H-DNA), four …
alternative (non-B) DNA structures, such as hairpins, cruciforms, triplexes (H-DNA), four …
Molecular insights into regulatory RNAs in the cellular machinery
S Yang, SH Kim, E Yang, M Kang, JY Joo - Experimental & Molecular …, 2024 - nature.com
It is apparent that various functional units within the cellular machinery are derived from
RNAs. The evolution of sequencing techniques has resulted in significant insights into …
RNAs. The evolution of sequencing techniques has resulted in significant insights into …
Nano-DMS-MaP allows isoform-specific RNA structure determination
Genome-wide measurements of RNA structure can be obtained using reagents that react
with unpaired bases, leading to adducts that can be identified by mutational profiling on next …
with unpaired bases, leading to adducts that can be identified by mutational profiling on next …
Interactive visualization of nanopore sequencing signal data with Squigualiser
Motivation Nanopore sequencing current signal data can be 'basecalled'into sequence
information or analysed directly, with the capacity to identify diverse molecular features, such …
information or analysed directly, with the capacity to identify diverse molecular features, such …
Isoform-specific RNA structure determination using Nano-DMS-MaP
RNA structure determination is essential to understand how RNA carries out its diverse
biological functions. In cells, RNA isoforms are readily expressed with partial variations …
biological functions. In cells, RNA isoforms are readily expressed with partial variations …
Direct RNA sequencing in plants: practical applications and future perspectives
XT Zhu, P Sanz-Jimenez, XT Ning, MT ul Qamar… - Plant …, 2024 - cell.com
The transcriptome serves as a bridge that links genomic variation and phenotype diversity. A
vast number of studies using next-generation RNA sequencing (RNA-seq) in the last two …
vast number of studies using next-generation RNA sequencing (RNA-seq) in the last two …
Design approaches to expand the toolkit for building cotranscriptionally encoded RNA strand displacement circuits
SW Schaffter, ME Wintenberg, TM Murphy… - ACS Synthetic …, 2023 - ACS Publications
Cotranscriptionally encoded RNA strand displacement (ctRSD) circuits are an emerging tool
for programmable molecular computation, with potential applications spanning in vitro …
for programmable molecular computation, with potential applications spanning in vitro …
Comprehensive transcriptome sequencing of silkworm Midguts: Uncovering extensive isoform diversity and alternative splicing in BmNPV-Sensitive and BmNPV …
M Tang, Y Liu, H Zhang, L Sun, P Lü, K Chen - Journal of Invertebrate …, 2024 - Elsevier
The silkworm, Bombyx mori, stands out as one of the few economically valuable insects
within the realm of model organisms. However, Bombyx mori nucleopolyhedrovirus …
within the realm of model organisms. However, Bombyx mori nucleopolyhedrovirus …
[HTML][HTML] Probing RNA structure and dynamics using nanopore and next generation sequencing
It has become increasingly evident that the structures RNAs adopt are conformationally
dynamic; the various structured states that RNAs sample govern their interactions with other …
dynamic; the various structured states that RNAs sample govern their interactions with other …
[PDF][PDF] Interactive visualization of nanopore sequencing signal data with Squigualiser
Motivation: Nanopore sequencing current signal data can be 'basecalled'into sequence
information or analysed directly, with the capacity to identify diverse molecular features, such …
information or analysed directly, with the capacity to identify diverse molecular features, such …