The mycobacterial cell envelope—a moving target

CL Dulberger, EJ Rubin, CC Boutte - Nature Reviews Microbiology, 2020 - nature.com
Mycobacterium tuberculosis, the leading cause of death due to infection, has a dynamic and
immunomodulatory cell envelope. The cell envelope structurally and functionally varies …

[HTML][HTML] Biofilms: Understanding the structure and contribution towards bacterial resistance in antibiotics

P Shree, CK Singh, KK Sodhi, JN Surya… - Medicine in …, 2023 - Elsevier
The biofilm is a bacterial colony wrapped in an auto-produced polymer matrix of
polysaccharides, proteins, and DNA. Bacterial biofilms cause persistent infections because …

Drug resistant tuberculosis: Implications for transmission, diagnosis, and disease management

D Liebenberg, BG Gordhan, BD Kana - Frontiers in cellular and …, 2022 - frontiersin.org
Drug resistant tuberculosis contributes significantly to the global burden of antimicrobial
resistance, often consuming a large proportion of the healthcare budget and associated …

Mechanistic origin of cell-size control and homeostasis in bacteria

F Si, G Le Treut, JT Sauls, S Vadia, PA Levin, S Jun - Current Biology, 2019 - cell.com
Evolutionarily divergent bacteria share a common phenomenological strategy for cell-size
homeostasis under steady-state conditions. In the presence of inherent physiological …

A constant size extension drives bacterial cell size homeostasis

M Campos, IV Surovtsev, S Kato, A Paintdakhi… - Cell, 2014 - cell.com
Cell size control is an intrinsic feature of the cell cycle. In bacteria, cell growth and division
are thought to be coupled through a cell size threshold. Here, we provide direct …

Staying in shape: the impact of cell shape on bacterial survival in diverse environments

DC Yang, KM Blair, NR Salama - Microbiology and Molecular …, 2016 - Am Soc Microbiol
Bacteria display an abundance of cellular forms and can change shape during their life
cycle. Many plausible models regarding the functional significance of cell morphology have …

Stress and host immunity amplify Mycobacterium tuberculosis phenotypic heterogeneity and induce nongrowing metabolically active forms

G Manina, N Dhar, JD McKinney - Cell host & microbe, 2015 - cell.com
Nonreplicating and metabolically quiescent bacteria are implicated in latent tuberculosis
infections and relapses following" sterilizing" chemotherapy. However, evidence linking …

How sisters grow apart: mycobacterial growth and division

KJ Kieser, EJ Rubin - Nature Reviews Microbiology, 2014 - nature.com
Mycobacterium tuberculosis, which is the aetiological agent of tuberculosis, owes much of its
success as a pathogen to its unique cell wall and unusual mechanism of growth, which …

Mycobacterium smegmatis: the vanguard of mycobacterial research

IL Sparks, KM Derbyshire, WR Jacobs Jr… - Journal of …, 2023 - Am Soc Microbiol
The genus Mycobacterium contains several slow-growing human pathogens, including
Mycobacterium tuberculosis, Mycobacterium leprae, and Mycobacterium avium …

Fundamental principles in bacterial physiology—history, recent progress, and the future with focus on cell size control: a review

S Jun, F Si, R Pugatch, M Scott - Reports on Progress in Physics, 2018 - iopscience.iop.org
Bacterial physiology is a branch of biology that aims to understand overarching principles of
cellular reproduction. Many important issues in bacterial physiology are inherently …