Animal models of asthma

GR Zosky, PD Sly - Clinical & Experimental Allergy, 2007 - Wiley Online Library
Animal models of asthma are a tool that allows studies to be conducted in the setting of an
intact immune and respiratory system. These models have highlighted the importance of T …

The alveolar macrophage: the forgotten cell in asthma

M Peters-Golden - American journal of respiratory cell and …, 2004 - atsjournals.org
As asthma and allergic respiratory diseases have reached epidemic proportions over the
last twenty years, research into the cellular and molecular pathogenesis of these disorders …

Female mice are more susceptible to the development of allergic airway inflammation than male mice

BN Melgert, DS Postma, I Kuipers… - Clinical & …, 2005 - Wiley Online Library
Background In humans the prevalence of asthma is higher among females than among
males after puberty. The reason for this phenomenon is not clear. Objective We tested the …

[HTML][HTML] Inhibition of oxidative stress, IL-13, and WNT/β-catenin in ovalbumin-sensitized rats by a novel organogel of Punica granatum seed oil saponifiable fraction

NZ Shaban, AS Mohammed, MM Abu-Serie… - Biomedicine & …, 2022 - Elsevier
Bronchial asthma is a chronic inflammatory disease marked by inflammation, oxidative
stress, and structural remodeling. Here, we prepared two pomegranate fractions from the …

Animal model of asthma, various methods and measured parameters: a methodological review

M Kianmeher, V Ghorani… - Iranian Journal of Allergy …, 2016 - ijaai.tums.ac.ir
Asthma is a chronic inflammatory disease of the airway with extensive airway remodeling.
The ethical issues associated with the studies in asthmatic patients, required development of …

[HTML][HTML] Regulation of the NF-κB signaling pathway and IL-13 in asthmatic rats by aerosol inhalation of the combined active constituents of Punica granatum juice and …

NZ Shaban, AA Sleem, MM Abu-Serie… - Biomedicine & …, 2022 - Elsevier
Bronchial asthma is a chronic inflammatory airway illness. For the first time, we evaluated
the proposed anti-asthmatic protective and therapeutic potency of inhaling Punica granatum …

Traditional medicinal plants conferring protection against ovalbumin-induced asthma in experimental animals: A review

S Azman, M Sekar, SR Bonam, SH Gan… - Journal of asthma …, 2021 - Taylor & Francis
Asthma is a chronic inflammatory disease of the respiratory tract in which the numerous
immune cells, including eosinophils, neutrophils, macrophages, T-lymphocytes, mast cells …

Short-term smoke exposure attenuates ovalbumin-induced airway inflammation in allergic mice

BN Melgert, DS Postma, M Geerlings… - American Journal of …, 2004 - atsjournals.org
Little is known about effects of smoking on airway inflammation in asthma. We tested the
hypothesis that smoking enhances established airway inflammation in a mouse model of …

Indoleamine 2, 3-dioxygenase–dependent tryptophan metabolites contribute to tolerance induction during allergen immunotherapy in a mouse model

YA Taher, BJA Piavaux, R Gras, BCAM van Esch… - Journal of Allergy and …, 2008 - Elsevier
BACKGROUND: The tryptophan-catabolizing enzyme indoleamine 2, 3-dioxygenase (IDO)
has been implicated in immune suppression and tolerance induction. OBJECTIVE: We …

Adverse effect of nano-silicon dioxide on lung function of rats with or without ovalbumin immunization

B Han, J Guo, T Abrahaley, L Qin, L Wang, Y Zheng… - PloS one, 2011 - journals.plos.org
Background The great advances of nanomaterials have brought out broad important
applications, but their possible nanotoxicity and risks have not been fully understood. It is …