Next-generation sequence assembly: four stages of data processing and computational challenges

S El-Metwally, T Hamza, M Zakaria… - PLoS computational …, 2013 - journals.plos.org
Decoding DNA symbols using next-generation sequencers was a major breakthrough in
genomic research. Despite the many advantages of next-generation sequencers, eg, the …

Next-generation sequencing technologies and their impact on microbial genomics

BM Forde, PW O'Toole - Briefings in functional genomics, 2013 - academic.oup.com
Next-generation sequencing technologies have had a dramatic impact in the field of
genomic research through the provision of a low cost, high-throughput alternative to …

A gene-by-gene population genomics platform: de novo assembly, annotation and genealogical analysis of 108 representative Neisseria meningitidis genomes

HB Bratcher, C Corton, KA Jolley, J Parkhill… - BMC genomics, 2014 - Springer
Background Highly parallel,'second generation'sequencing technologies have rapidly
expanded the number of bacterial whole genome sequences available for study, permitting …

Cluster editing

S Böcker, J Baumbach - Conference on Computability in Europe, 2013 - Springer
Abstract The Cluster Editing problem asks to transform a graph into a disjoint union of
cliques using a minimum number of edge modifications. Although the problem has been …

The detection of KPC-2, NDM-1, and VIM-2 carbapenemases in international clones isolated from fresh vegetables highlights an emerging food safety issue

JPR Furlan, R Lopes, MS Ramos… - International Journal of …, 2024 - Elsevier
Resistance to carbapenems emerged in clinical settings and has rapidly spread to other
sectors, such as food and the environment, representing a One Health problem. In this …

Genetic plurality of blaKPC-2-harboring plasmids in high-risk clones of Klebsiella pneumoniae of environmental origin

JPR Furlan, R da Silva Rosa, MS Ramos… - Science of The Total …, 2023 - Elsevier
International high-risk clones of Klebsiella pneumoniae are important human pathogens that
are spreading to the environment. In the COVID-19 pandemic scenario, the frequency of …

Convergence of mcr-1 and broad-spectrum β-lactamase genes in Escherichia coli strains from the environmental sector

JPR Furlan, R da Silva Rosa, MS Ramos, R Lopes… - Environmental …, 2024 - Elsevier
The mcr-type gene encodes the main plasmid-mediated mechanism of colistin resistance
and has been reported in several bacterial species obtained from different sources …

CoryneRegNet 6.0—Updated database content, new analysis methods and novel features focusing on community demands

J Pauling, R Röttger, A Tauch, V Azevedo… - Nucleic acids …, 2012 - academic.oup.com
Post-genomic analysis techniques such as next-generation sequencing have produced vast
amounts of data about micro organisms including genetic sequences, their functional …

Genome sequence of Exiguobacterium antarcticum B7, isolated from a biofilm in Ginger Lake, King George Island, Antarctica

AR Carneiro, RTJ Ramos, H Dall'Agnol, AC Pinto… - 2012 - Am Soc Microbiol
Exiguobacterium antarcticum is a psychotropic bacterium isolated for the first time from
microbial mats of Lake Fryxell in Antarctica. Many organisms of the genus Exiguobacterium …

Genome sequence of Corynebacterium pseudotuberculosis biovar equi strain 258 and prediction of antigenic targets to improve biotechnological vaccine production

SC Soares, E Trost, RTJ Ramos, AR Carneiro… - Journal of …, 2013 - Elsevier
Corynebacterium pseudotuberculosis is the causative agent of several veterinary diseases
in a broad range of economically important hosts, which can vary from caseous …