1, 2, 3-Triazole-containing hybrids as potential anticancer agents: Current developments, action mechanisms and structure-activity relationships
Z Xu, SJ Zhao, Y Liu - European journal of medicinal chemistry, 2019 - Elsevier
Anticancer agents are critical for the cancer treatment, but side effects and the drug
resistance associated with the currently used anticancer agents create an urgent need to …
resistance associated with the currently used anticancer agents create an urgent need to …
1, 2, 3-Triazole-containing compounds as anti–lung cancer agents: Current developments, mechanisms of action, and structure–activity relationship
T Liang, X Sun, W Li, G Hou, F Gao - Frontiers in pharmacology, 2021 - frontiersin.org
Lung cancer is the most common malignancy and leads to around one-quarter of all cancer
deaths. Great advances have been achieved in the treatment of lung cancer with novel …
deaths. Great advances have been achieved in the treatment of lung cancer with novel …
Ramachary-Bressy-Wang [3+ 2] cycloaddition reaction: Synthesis of fully decorated 1, 2, 3-triazoles as potent anticancer and EGFR inhibitors
M Kumar, SK Nukala, NS Thirukovela… - Journal of Molecular …, 2022 - Elsevier
A general strategy was developed for the synthesis of new fully decorated 1, 2, 3-triazoles
(5a-m & 6a-e) containing coumarine and sulfonyl-benzimidazole from 3-(2-((1-methyl-1H …
(5a-m & 6a-e) containing coumarine and sulfonyl-benzimidazole from 3-(2-((1-methyl-1H …
Ionic Liquids for Green Synthesis of 1, 2, 3-Triazoles: A systematic Review
The exponentially increasing use of hazardous traditional organic solvents and catalysts for
more accessible synthesis of important heterocycles useful for humankind in various fields …
more accessible synthesis of important heterocycles useful for humankind in various fields …
Fused benzo [1, 3] thiazine-1, 2, 3-triazole hybrids: Microwave-assisted one-pot synthesis, in vitro antibacterial, antibiofilm, and in silico ADME studies
ER Sucharitha, TM Krishna, R Manchal… - Bioorganic & Medicinal …, 2021 - Elsevier
In this paper, we report an efficient one-pot three-component reaction sequences comprising
Cu (I)-catalyzed 1, 3-dipolar cycloaddition (CuAAC) followed by Cu-catalyzed arylation of …
Cu (I)-catalyzed 1, 3-dipolar cycloaddition (CuAAC) followed by Cu-catalyzed arylation of …
Benzothiazole-[1, 2, 3] triazolo [5, 1-a] isoindoles: Synthesis, anticancer activity, bioavailability and in silico studies against Gama-Tubulin protein
We, herein, reported the CuI catalyzed synthesis of some novel fused benzothiazole-1, 2, 3-
triazole hybrids (5a-5o) in one-pot. The in vitro anticancer activity of these compounds …
triazole hybrids (5a-5o) in one-pot. The in vitro anticancer activity of these compounds …
A concise review of multicomponent reactions using novel heterogeneous catalysts under microwave irradiation
Multi-component reactions for the construction of heterocycles have been fascinated by
microwave energy as an alternative technique of heating, owing to the advantages over …
microwave energy as an alternative technique of heating, owing to the advantages over …
Synthesis and biological evaluation of novel [1, 2, 3] triazolo-pyrrolo [1, 2-a] pyrido [4, 3-d] pyrimidines as EGFR targeting anticancer agents
SR Bandi, N Kavitha, SK Nukala… - Journal of Molecular …, 2023 - Elsevier
Herein, we synthesized some new fused [1, 2, 3] triazolo-pyrrolo [1, 2-a] pyrido [4, 3-d]
pyrimidines via click chemistry followed by carbon-carbon bond coupling as key approach …
pyrimidines via click chemistry followed by carbon-carbon bond coupling as key approach …
Synthesis and biological evaluation of coumarine-imidazo [1, 2-c][1, 2, 3] triazoles: PEG-400 mediated one-pot reaction under ultrasonic irradiation
R Samala, SK Nukala, R Manchal, VR Nagavelli… - Journal of Molecular …, 2023 - Elsevier
Synthetic chemists have organized easy and effective ways for perfect synthesis in response
to the requirement for scaffolds that are crucial for medical applications. To investigate the …
to the requirement for scaffolds that are crucial for medical applications. To investigate the …
Microwave accelerated green approach for tailored 1, 2, 3–triazoles via CuAAC
N George, G Singh, R Singh, G Singh, A Devi… - Sustainable Chemistry …, 2022 - Elsevier
The persistent deterioration of our environmental assets has initiated 'a push'among the
scientific community for increased reliance on eco-friendly methodologies minimizing the …
scientific community for increased reliance on eco-friendly methodologies minimizing the …