Back to basics: the neuronal substrates and mechanisms that underlie the electroencephalogram in premature neonates

F Wallois, L Routier, C Heberlé… - Neurophysiologie …, 2021 - Elsevier
Electroencephalography is the only clinically available technique that can address the
premature neonate normal and pathological functional development week after week. The …

Early brain activity: translations between bedside and laboratory

HJ Luhmann, PO Kanold, Z Molnár… - Progress in neurobiology, 2022 - Elsevier
Neural activity is both a driver of brain development and a readout of developmental
processes. Changes in neuronal activity are therefore both the cause and consequence of …

Machine learning for the early prediction of infants with electrographic seizures in neonatal hypoxic‐ischemic encephalopathy

AM Pavel, JM O'Toole, J Proietti, V Livingstone… - …, 2023 - Wiley Online Library
Objective To assess if early clinical and electroencephalography (EEG) features predict later
seizure development in infants with hypoxic‐ischemic encephalopathy (HIE). Methods …

Time-varying EEG correlations improve automated neonatal seizure detection

KT Tapani, S Vanhatalo… - International journal of …, 2019 - World Scientific
The aim of this study was to develop methods for detecting the nonstationary periodic
characteristics of neonatal electroencephalographic (EEG) seizures by adapting estimates …

Deep learning for EEG seizure detection in preterm infants

A O'Shea, R Ahmed, G Lightbody… - … journal of neural …, 2021 - World Scientific
EEG is the gold standard for seizure detection in the newborn infant, but EEG interpretation
in the preterm group is particularly challenging; trained experts are scarce and the task of …

NEURAL: quantitative features for newborn EEG using Matlab

JMO Toole, GB Boylan - arXiv preprint arXiv:1704.05694, 2017 - arxiv.org
Background: For newborn infants in critical care, continuous monitoring of brain function can
help identify infants at-risk of brain injury. Quantitative features allow a consistent and …

Clamping the umbilical cord in premature deliveries (CUPiD): neuromonitoring in the immediate newborn period in a randomized, controlled trial of preterm infants …

D Finn, DH Ryan, A Pavel, JM O'Toole… - The Journal of …, 2019 - Elsevier
Objective To compare cerebral activity and oxygenation in preterm infants (< 32 weeks of
gestation) randomized to different cord clamping strategies. Study design Preterm infants …

Quantitative preterm EEG analysis: the need for caution in using modern data science techniques

JM O'Toole, GB Boylan - Frontiers in pediatrics, 2019 - frontiersin.org
Hemodynamic changes during neonatal transition increase the vulnerability of the preterm
brain to injury. Real-time monitoring of brain function during this period would help identify …

Electroencephalographic studies in growth-restricted and small-for-gestational-age neonates

NJ Stevenson, MM Lai, HE Starkman, PB Colditz… - Pediatric …, 2022 - nature.com
Foetal growth restriction (FGR) and being born small for gestational age (SGA) are
associated with neurodevelopmental delay. Early diagnosis of neurological damage is …

Temporal evolution of quantitative EEG within 3 days of birth in early preterm infants

JM O'Toole, E Pavlidis, I Korotchikova, GB Boylan… - Scientific reports, 2019 - nature.com
For the premature newborn, little is known about changes in brain activity during transition to
extra-uterine life. We aim to quantify these changes in relation to the longer-term maturation …