Accurate genome assembly is hampered by repetitive regions. Although long single
molecule sequencing reads are better able to resolve genomic repeats than short-read data …

Highlights•Plasmid evolution reviewed from the perspective of plasmids.•Mobility, stability,
and indispensability largely determine plasmid lifestyles.•Changes in plasmid traits facilitate …

Replication of the bacterial chromosome initiates at a single origin of replication that is
called oriC. This occurs via the concerted action of numerous proteins, including DnaA …

The separation and segregation of newly replicated bacterial chromosomes can be
constrained by the formation of circular chromosome dimers caused by crossing over during …

The last three decades have witnessed an explosion of discoveries about the mechanistic
details of binary fission in model bacteria such as Escherichia coli, Bacillus subtilis, and …

Bacterial species from diverse phyla contain multiple replicons, yet how these multipartite
genomes are organized and segregated during the cell cycle remains poorly understood …

Spatial ordering of macromolecular components inside cells is important for cellular
physiology and replication. In bacteria, ParA/B systems are known to generate various …

Overgrowth of filamentous bacteria in activated sludge wastewater treatment plants
(WWTPs) leads to impaired sludge settleability, a condition known as bulking, which is a …

Dynamic protein gradients are exploited for the spatial organization and segregation of
replicated chromosomes. However, mechanisms of protein gradient formation and how that …

Control of chromosome replication involves a common set of regulators in eukaryotes,
whereas bacteria with divided genomes use chromosome-specific regulators. How bacterial …