Aerobic glycolysis is an emerging hallmark of many human cancers, as cancer cells are
defined as a “metabolically abnormal system”. Carbohydrates are metabolically …

Triple-negative breast cancer (TNBC) is a subtype of breast cancer that is highly aggressive
and hypoxic compared with other subtypes. The role of hypoxia inducible factor 1α (HIF-1α) …

Highlights•Tumor cells increase their metabolic rates as well as glucose uptake to maintain
amplified proliferation,•Consequently, tumor cells switch from mitochondrial oxidative …

Redox balance is associated with the regulation of several cell signalling pathways and
functions. In fact, under physiological conditions, cells maintain a balance between oxidant …

The predominant use of glucose anaerobically by cancer cells (Warburg effect) may be the
most important characteristic the majority of these cells have in common and, therefore, a …

Alpha-enolase (ENO1) is a metabolic enzyme involved in the synthesis of pyruvate. It also
acts as a plasminogen receptor and mediates the activation of plasmin and extracellular …

Simple Summary One hundred years ago, it was discovered that some cancer cells have a
different metabolism from normal cells. This alternative metabolism is called the Warburg …

Immune cells undergo different metabolic pathways or immunometabolisms to interact with
various antigens. Immunometabolism links immunological and metabolic processes and is …

MicroRNAs (miRNAs) are endogenous and small non-coding RNAs that have been
identified as mediators of tumor suppression as well as stress responses mediated by p53 …

Preclinical studies and clinical trials have emphasized the decisive role of lipid metabolism
in tumor proliferation and metastasis. This systematic review aimed to explore the existing …