Pemphigus: current and future therapeutic strategies

D Didona, R Maglie, R Eming, M Hertl - Frontiers in immunology, 2019 - frontiersin.org
Pemphigus encompasses a heterogeneous group of autoimmune blistering diseases, which
affect both mucous membranes and the skin. The disease usually runs a chronic-relapsing …

Pemphigus: a comprehensive review on pathogenesis, clinical presentation and novel therapeutic approaches

R Pollmann, T Schmidt, R Eming, M Hertl - Clinical reviews in allergy & …, 2018 - Springer
Pemphigus is a group of rare, potentially devastating autoimmune diseases of the skin and
mucous membranes with high morbidity and potentially lethal outcome. The major clinical …

Pemphigus autoimmunity: hypotheses and realities

SA Grando - Autoimmunity, 2012 - Taylor & Francis
The goal of contemporary research in pemphigus vulgaris and pemphigus foliaceus is to
achieve and maintain clinical remission without corticosteroids. Recent advances of …

[HTML][HTML] Mechanisms causing loss of keratinocyte cohesion in pemphigus

V Spindler, R Eming, E Schmidt, M Amagai… - Journal of Investigative …, 2018 - Elsevier
The autoimmune blistering skin disease pemphigus is caused by IgG autoantibodies against
desmosomal cadherins, but the precise mechanisms are in part a matter of controversial …

Alarmins in autoimmune diseases

MG Danieli, E Antonelli, MA Piga, I Claudi… - Autoimmunity …, 2022 - Elsevier
Alarmins are endogenous, constitutively expressed, chemotacting and immune activating
proteins or peptides released because of non-programmed cell death (ie infections, trauma …

Pemphigus vulgaris: update on etiopathogenesis, oral manifestations, and management

C Scully, SJ Challacombe - Critical Reviews in Oral Biology …, 2002 - journals.sagepub.com
Pemphigus is a group of potentially life-threatening diseases characterized by cutaneous
and mucosal blistering. There is a fairly strong genetic background to pemphigus with …

The desmosome and pemphigus

J Waschke - Histochemistry and cell biology, 2008 - Springer
Desmosomes are patch-like intercellular adhering junctions (“maculae adherentes”), which,
in concert with the related adherens junctions, provide the mechanical strength to …

The genetics of pemphigus vulgaris

D Vodo, O Sarig, E Sprecher - Frontiers in medicine, 2018 - frontiersin.org
Pemphigus vulgaris (PV) is a severe autoimmune blistering disease caused by auto-
antibodies (auto-Abs) directed against epithelial desmosomal components and leading to …

[PDF][PDF] Mortality and cause of death in patients with pemphigus

K Kridin, SZ Sagi, R Bergman - Acta dermato …, 2017 - medicaljournalssweden.se
All-cause and cause-specific mortality among patients with pemphigus compared with the
general population is yet to be established. This study investigated overall mortality and …

Activation of autoimmunity following use of immunostimulatory herbal supplements

AN Lee, VP Werth - Archives of Dermatology, 2004 - jamanetwork.com
Background Evidence for the scientific basis of purported therapeutic effects and adverse
effects of herbal supplements continues to grow. Many herbal supplements are touted for …