In patients with decompensated cirrhosis, sarcopenia and frailty are prevalent. Although
several definitions exist for these terms, in the field of hepatology, sarcopenia has commonly …

Cortisol is a steroid hormone that is released from the body in response to stress. Although a
moderate level of cortisol secretion can help the body maintain homeostasis, excessive …

This is the first American Association for the Study of Liver Diseases (AASLD) practice
guidance on the management of malnutrition, frailty, and sarcopenia in patients with …

Background & Aims The association between sarcopenia and prognosis in patients with
cirrhosis remains to be determined. In this study, we aimed to quantify the association …

Background Sarcopenia is frequently found in patients with cirrhosis and is associated with
liver dysfunction, cirrhosis-related complications, and poorer quality of life. Purpose To …

With the increasing incidence of non-alcoholic fatty liver disease (NAFLD) and the aging of
the population, sarcopenia is attracting attention as one of the pathological conditions …

Background and Aims Cholestatic liver injury leads to cell death and subsequent
inflammation and fibrosis. As shown for primary biliary cholangitis (PBC), the mechanisms …

In this review article, we discuss the model for end-stage liver disease (MELD) score and its
dual purpose in general and transplant hepatology. As the landscape of liver disease and …

Patients with liver cirrhosis and, in particular, those with liver failure are at high risk of
reduced muscle mass and strength/function, otherwise known as sarcopenia. Sarcopenia is …

Frailty is a decline in functional reserve across multiple physiological systems. A key
component of frailty is sarcopenia, which denotes a loss of skeletal muscle mass and …