Alpha-2 agonists, such as xylazine, clonidine, romifidine, detomidine, medetomidine, and
dexmedetomidine, are potent analgesic drugs that also induce physiologic and behavioral …

Sedatives and tranquilizers play an important role in day‐to‐day veterinary practice. The use
of these medications as part of an anesthetic regimen has many advantages, including, but …

As Act. The cardiovascular effects of medetomidine, detomidine, and xylazine in horses
were studied. Fifteen horses, whose right carotid arteries had previously bcen surgically …

The need for sedation or general anesthesia of cattle is relatively common in bovine
practice. Inhalation anesthesia is occasionally used in calves, but in larger animals this can …

Opioid analgesic drugs Page 318 CHAPTER 12 OPIOID ANALGESIC DRUGS BUTCH
KUKANICH AND MARK G. PAPICH Introduction Background on Opioids Opioid Role in …

Reasons for performing study: Detomidine hydrochloride is used to provide sedation,
muscle relaxation and analgesia in horses, but a lack of information pertaining to plasma …

OBJECTIVE To determine the pharmacokinetics and pharmacodynamics of
dexmedetomidine after IM administration in dogs. ANIMALS 6 healthy adult purpose-bred …

Objective To investigate plasma drug concentrations and the effect of MK-467 (L-659′ 066)
on sedation, heart rate and gut motility in horses sedated with intravenous (IV) detomidine …

Reasons for performing study: Detomidine is commonly used iv for sedation and analgesia
in horses, but the pharmacokinetics and metabolism of this drug have not been well …

Objective To assess the effectiveness of a detomidine infusion technique to provide standing
chemical restraint in the horse. Design Retrospective study. Animals Fifty‐one adult horses …